IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with LTBP1 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Rabbit anti-Human, mouse LTBP1 Polyclonal Antibody | anti-LTBP1 antibody
LTBP1 Antibody (C-term)
Reactivity
Human, mouse
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
LTBP1, Antibody; LTBP1 Antibody (C-term); Latent-transforming growth factor beta-binding protein 1; LTBP-1; Transforming growth factor beta-1-binding protein 1; TGF-beta1-BP-1; LTBP1; anti-LTBP1 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This LTBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1493-1525 amino acids from the C-terminal region of human LTBP1.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Sequence Positions
1493-1525
Sequence Length
1395
Applicable Applications for anti-LTBP1 antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Function
May be involved in the assembly, secretionand targeting of TGFB1 to sites at which it is stored and/or activated. May play critical
roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM).
Cellular location
Cellular Location
Tissue Location
Expressed in the aorta (at protein level).
Isoform Long is found in fibroblasts
Cellular location
Secreted, secreted, extracellular space, extracellular matrix.
Tissue location
Expressed in the aorta (at protein level). PubMed: 1 729309). Isoform Long: Expressed in fibroblasts (PubMed: 17293099).
Preparation and Storage
Maintain refrigerated at 2-8 degree for up to weeks. For long term storage store at -20 degree in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with LTBP1 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with LTBP1 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
WB (Western Blot)
(LTBP1 Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the LTBP1 antibody detected the LTBP1 protein (arrow).)
WB (Western Blot)
(LTBP1 Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the LTBP1 antibody detected the LTBP1 protein (arrow).)
Related Product Information for anti-LTBP1 antibody
LTBP1 may be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. This protein may play critical roles in controlling and directing the activity of TGFB1, and it may have a structural role in the extra cellular matrix (ECM).
Product Categories/Family for anti-LTBP1 antibody
References
Olofsson A., J. Biol. Chem. 270:31294-31297(1995)
Kanzaki T., Cell 61:1051-1061(1990)
Isogai Z., J. Biol. Chem. 278:2750-2757(2003)
Oklu R., Biochem. J. 352:601-610(2000)
Kanzaki T., Cell 61:1051-1061(1990)
Isogai Z., J. Biol. Chem. 278:2750-2757(2003)
Oklu R., Biochem. J. 352:601-610(2000)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
latent-transforming growth factor beta-binding protein 1 isoform LTBP-1S
NCBI Official Synonym Full Names
latent transforming growth factor beta binding protein 1
NCBI Official Symbol
LTBP1
NCBI Protein Information
latent-transforming growth factor beta-binding protein 1
UniProt Protein Name
Latent-transforming growth factor beta-binding protein 1
UniProt Gene Name
LTBP1
UniProt Synonym Gene Names
LTBP-1; TGF-beta1-BP-1
UniProt Entry Name
LTBP1_HUMAN
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Product Notes
The LTBP1 ltbp1 (Catalog #AAA285804) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1493-1525. The LTBP1 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LTBP1 can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the LTBP1 ltbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LTBP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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