WB (Western Blot)
(Western blotAll lanes: Loxl2 antibody at 14ug/mlLane 1: 293T whole cell lysateLane 2: A549 whole cell lysateLane 3: A431 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 88,82 kDaObserved band size: 87 kDa)
Rabbit anti-Mouse, Human Lysyl oxidase homolog 2 Polyclonal Antibody | anti-Loxl2 antibody
Rabbit anti-mouse Lysyl oxidase homolog 2 polyclonal Antibody
Gene Names
Loxl2; 1110004B06Rik; 4930526G11Rik; 9430067E15Rik
Reactivity
Mouse, Human
Applications
Western Blot, ELISA
Purity
>95%, Protein G purified
Synonyms
Lysyl oxidase homolog 2, Antibody; Rabbit anti-mouse Lysyl oxidase homolog 2 polyclonal Antibody; Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2), Loxl2; anti-Loxl2 antibody
Host
Rabbit
Reactivity
Mouse, Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Applicable Applications for anti-Loxl2 antibody
WB (Western Blot), ELISA
Immunogen
Recombinant Mouse Lysyl oxidase homolog 2 protein (26-776AA)
Conjugate
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Species
Mus musculus (Mouse)
Research Area
Signal Transduction
Target Names
Loxl2
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
WB (Western Blot)
(Western blotAll lanes: Loxl2 antibody at 14ug/mlLane 1: 293T whole cell lysateLane 2: A549 whole cell lysateLane 3: A431 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 88,82 kDaObserved band size: 87 kDa)
WB (Western Blot)
(Western blotAll lanes: Loxl2 antibody at 14ug/mlLane 1: 293T whole cell lysateLane 2: A549 whole cell lysateLane 3: A431 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 88,82 kDaObserved band size: 87 kDa)
Related Product Information for anti-Loxl2 antibody
Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated Lys-4 of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Involved in epithelial to mesenchymal transition (EMT) via interaction with SNAI1 and participates in repression of E-cadherin, probably by mediating deamination of histone H3 By similarity. Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
lysyl oxidase homolog 2
NCBI Official Synonym Full Names
lysyl oxidase-like 2
NCBI Official Symbol
Loxl2
NCBI Official Synonym Symbols
1110004B06Rik; 4930526G11Rik; 9430067E15Rik
NCBI Protein Information
lysyl oxidase homolog 2
UniProt Protein Name
Lysyl oxidase homolog 2
UniProt Gene Name
Loxl2
UniProt Entry Name
LOXL2_MOUSE
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Product Notes
The Loxl2 loxl2 (Catalog #AAA118743) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-mouse Lysyl oxidase homolog 2 polyclonal Antibody reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's Lysyl oxidase homolog 2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the Loxl2 loxl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lysyl oxidase homolog 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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