IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Rabbit anti-Human MAGEA2 Polyclonal Antibody | anti-MAGEA2 antibody
MAGEA2 Antibody (N-term)
Gene Names
MAGEA2; CT1.2; MAGE2; MAGEA2A
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MAGEA2, Antibody; MAGEA2 Antibody (N-term); Melanoma-associated antigen 2; Cancer/testis antigen 12; CT12; MAGE-2 antigen; MAGEA2; MAGE2; MAGEA2A; anti-MAGEA2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MAGEA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the N-terminal region of human MAGEA2.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
81-108
Sequence Length
314
Applicable Applications for anti-MAGEA2 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
WB (Western Blot)
(The anti-MAGEA2 N-term Antibody is used in Western blot to detect MAGEA2 in HL60 lysate.)
WB (Western Blot)
(The anti-MAGEA2 N-term Antibody is used in Western blot to detect MAGEA2 in HL60 lysate.)
Related Product Information for anti-MAGEA2 antibody
MAGEA2 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci.
Product Categories/Family for anti-MAGEA2 antibody
References
Rogner, U.C., et al., Genomics 29(3):725-731 (1995).
De Smet, C., et al., Immunogenetics 39(2):121-129 (1994).
De Plaen, E., et al., Immunogenetics 40(5):360-369 (1994).
van der Bruggen, P., et al., Science 254(5038):1643-1647 (1991).
De Smet, C., et al., Immunogenetics 39(2):121-129 (1994).
De Plaen, E., et al., Immunogenetics 40(5):360-369 (1994).
van der Bruggen, P., et al., Science 254(5038):1643-1647 (1991).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35055
NCBI Official Full Name
melanoma-associated antigen 2
NCBI Official Synonym Full Names
melanoma antigen family A2
NCBI Official Symbol
MAGEA2
NCBI Official Synonym Symbols
CT1.2; MAGE2; MAGEA2A
NCBI Protein Information
melanoma-associated antigen 2
UniProt Protein Name
Melanoma-associated antigen 2
UniProt Gene Name
MAGEA2
UniProt Synonym Gene Names
MAGE2; MAGEA2A; CT1.2
UniProt Entry Name
MAGA2_HUMAN
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Product Notes
The MAGEA2 magea2 (Catalog #AAA285574) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 81-108. The MAGEA2 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MAGEA2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the MAGEA2 magea2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAGEA2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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