IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using MANF Polyclonal Antibody at dilution 1:70)
Rabbit MANF Polyclonal Antibody | anti-MANF antibody
MANF Polyclonal Antibody
Gene Names
MANF; ARP; ARMET
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, ELISA
Purity
Antigen affinity purification
Synonyms
MANF, Antibody; MANF Polyclonal Antibody; ARP; ARMET; anti-MANF antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
2.5mg/mL (varies by lot)
Sequence Length
185
Applicable Applications for anti-MANF antibody
IHC (Immunohistochemistry), ELISA
Immunogen
Synthetic peptide of human MANF
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using MANF Polyclonal Antibody at dilution 1:70)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using MANF Polyclonal Antibody at dilution 1:70)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MANF Polyclonal Antibody at dilution 1:70)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MANF Polyclonal Antibody at dilution 1:70)
Related Product Information for anti-MANF antibody
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
Product Categories/Family for anti-MANF antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,700 Da
NCBI Official Full Name
mesencephalic astrocyte-derived neurotrophic factor
NCBI Official Synonym Full Names
mesencephalic astrocyte-derived neurotrophic factor
NCBI Official Symbol
MANF
NCBI Official Synonym Symbols
ARP; ARMET
NCBI Protein Information
mesencephalic astrocyte-derived neurotrophic factor; arginine-rich, mutated in early stage tumors
UniProt Protein Name
Mesencephalic astrocyte-derived neurotrophic factor
UniProt Gene Name
MANF
UniProt Synonym Gene Names
ARMET; ARP
UniProt Entry Name
MANF_HUMAN
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Product Notes
The MANF manf (Catalog #AAA166459) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MANF Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MANF can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the MANF manf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MANF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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