Rabbit anti-Human MAP1LC3C Polyclonal Antibody | anti-MAP1LC3C antibody

MAP1LC3C Antibody

Cat. Num. AAA40571

• Gene Names: MAP1LC3C; LC3C; ATG8J
• Reactivity: Human
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: MAP1LC3C antibody is affinity chromatography purified via peptide column.
• Synonyms: MAP1LC3C, Antibody; MAP1LC3C Antibody; MAP1LC3C; LC3C; ATG8JAutophagy-related protein LC3 C; microtubule-associated protein 1 light chain 3 gamma; anti-MAP1LC3C antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: MAP1LC3C antibody is human, mouse and rat reactive. Multiple isoforms MAP1LC3C are known to exist. MAP1LC3C antibody is predicted to not cross-react with MAP1LC3A or MAP1LC3B.
• Purity/Purification: MAP1LC3C antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 147

• Applicable Applications for anti-MAP1LC3C antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: MAP1LC3C antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MAP1LC3C.
• Buffer: MAP1LC3C antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: MAP1LC3C antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.

IF (Immunofluorescence)

(Immunofluorescence of MAP1LC3C in human brain tissue with MAP1LC3C antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of MAP1LC3C in human brain tissue with MAP1LC3C antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of MAP1LC3C in human brain tissue lysate with MAP1LC3C antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)

Related Product Information for anti-MAP1LC3C antibody

Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1). MAP1LC3C belongs to the MAP1 LC3 family of proteins that form mature complexes with MAP1A and MAP1B which are thought to be important in the formation and development of axons and dendrites (2). MAP1LC3C is one of three isoforms of MAP1LC3, the mammalian homolog of yeast ATG8, an essential autophagy protein. These isoforms exhibit distinct expression patterns and MAP1LC3C, like MAP1LC3A but not MAP1LC3B, is post-translationally modified, suggesting the three isoforms may have different physiological functions (3).

NCBI and Uniprot Product Information

• NCBI GI #: 51972260
• NCBI GeneID: 440738
• NCBI Accession #: NP_001004343
• NCBI GenBank Nucleotide #: NM_001004343.2
• UniProt Accession #: Q9BXW4; A0PJY8; A2RUP0
• Molecular Weight: Predicted: 16 kDa; ; Observed: 16 kDa
• NCBI Official Full Name: microtubule-associated proteins 1A/1B light chain 3C
• NCBI Official Synonym Full Names: microtubule-associated protein 1 light chain 3 gamma
• NCBI Official Symbol: MAP1LC3C
• NCBI Official Synonym Symbols: LC3C; ATG8J
• NCBI Protein Information: microtubule-associated proteins 1A/1B light chain 3C; MAP1A/MAP1B LC3 C; LC3-like protein 2; MAP1A/MAP1B light chain 3 C; autophagy-related protein LC3 C; MAP1 light chain 3-like protein 2; MAP1 light chain 3-like protein 3; autophagy-related ubiquitin-like modifier LC3 C
• UniProt Protein Name: Microtubule-associated proteins 1A/1B light chain 3C
• UniProt Gene Name: MAP1LC3C
• UniProt Synonym Gene Names: MAP1A/MAP1B LC3 C
• UniProt Entry Name: MLP3C_HUMAN