IHC (Immunohiostchemistry)
(Immunohistochemistry of MAPKAP1 in human skeletal muscle tissue with MAPKAP1 antibody at 2.5 ug/mL.)
Rabbit MAPKAP1 Polyclonal Antibody | anti-MAPKAP1 antibody
MAPKAP1 Antibody
Gene Names
MAPKAP1; MIP1; SIN1; JC310; SIN1b; SIN1g
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
MAPKAP1, Antibody; MAPKAP1 Antibody; Mitogen activated protein kinase associated protein 1, Sin1, stress-activated protein kinase-interacting protein 1, MIP1; anti-MAPKAP1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
522
Applicable Applications for anti-MAPKAP1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 19 amino acid peptide from near the amino terminus of human MAPKAP1.
Target Name
MAPKAP1
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of MAPKAP1 in human skeletal muscle tissue with MAPKAP1 antibody at 2.5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of MAPKAP1 in human skeletal muscle tissue with MAPKAP1 antibody at 2.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of MAPKAP1 in human skeletal muscle tissue lysate with MAPKAP1 antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of MAPKAP1 in human skeletal muscle tissue lysate with MAPKAP1 antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.)
Related Product Information for anti-MAPKAP1 antibody
MAPKAP1 was initially identified as the human homolog of S. pombe SIN1. Recent evidence has shown that it identical to Mip1, a protein that interacts with MEKK2, a member of the mitogen-activated protein kinase (MAPK) intracellular signaling network. MAPKAP1 is thought to prevent MEKK2 activation and dimerization by forming a complex with the inactive and non-phosphorylated MEKK2, thereby blocking the JNK1/2, ERK1/2, p38 and ERK5 MAPKs. MAPKAP1 has also been shown to play a role in the TOR signaling process, a pathway that is involved in controlling cell growth and proliferation in response to environmental cues such as nutrients, growth factors and hormones. Experiments showed that MAPKAP1 helped to maintain the TOR/rictor assembly but not the TOR/RAPTOR complex, which allowed specific phosphorylation of Akt, a kinase that is believed to couple the growth factor-PI3K signaling pathway to the nutrient-regulated TOR signaling pathway. Multiple alternatively spliced isoforms of MAPKAP1 have been identified.
Product Categories/Family for anti-MAPKAP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41,838 Da
NCBI Official Full Name
target of rapamycin complex 2 subunit MAPKAP1 isoform 1
NCBI Official Synonym Full Names
mitogen-activated protein kinase associated protein 1
NCBI Official Symbol
MAPKAP1
NCBI Official Synonym Symbols
MIP1; SIN1; JC310; SIN1b; SIN1g
NCBI Protein Information
target of rapamycin complex 2 subunit MAPKAP1
UniProt Protein Name
Target of rapamycin complex 2 subunit MAPKAP1
UniProt Gene Name
MAPKAP1
UniProt Synonym Gene Names
MIP1; SIN1; TORC2 subunit MAPKAP1; SAPK-interacting protein 1; mSIN1
UniProt Entry Name
SIN1_HUMAN
Similar Products
Product Notes
The MAPKAP1 mapkap1 (Catalog #AAA303642) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAPKAP1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MAPKAP1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the MAPKAP1 mapkap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAPKAP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.