IHC (Immunohistochemisry)
(MAPT/Tau Antibody-Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit anti-Human MAPT/Tau Polyclonal Antibody | anti-MAPT antibody
MAPT/Tau Rabbit anti-Human Polyclonal Antibody
Gene Names
MAPT; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17
Reactivity
Human
Applications
Immunohistochemistry
Purity
Immunoaffinity purified
Synonyms
MAPT/Tau, Antibody; MAPT/Tau Rabbit anti-Human Polyclonal Antibody; PathPlus MAPT/Tau Antibody; MAPT; FTDP-17; MSTD; Neurofibrillary tangle protein; PHF-tau; MTBT2; PPND; DDPAC; MAPTL; MTBT1; Paired helical filament-tau; TAU; anti-MAPT antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.1% Sodium Azide
Concentration
0.9mg/ml (varies by lot)
Applicable Applications for anti-MAPT antibody
IHC (Immunohistochemistry)
Target
Human MAPT/Tau
Immunogen
LP-12406, synthetic peptide
Conjugation
Unconjugated
Preparation and Storage
Aliquot and store undiluted at -20 degree C or below for up to 1 year. Can be stored undiluted at 4 degree C for up to 1 month. Avoid freeze-thaw cycles.
IHC (Immunohistochemisry)
(MAPT/Tau Antibody-Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemisry)
(MAPT/Tau Antibody-Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(MAPT/Tau Antibody-Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(MAPT/Tau Antibody-Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(MAPT/Tau Antibody-Human Small Intestine, Ganglia: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(MAPT/Tau Antibody-Human Small Intestine, Ganglia: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-MAPT antibody
Tau antibody is an unconjugated rabbit polyclonal antibody to Tau (MAPT) from human. Validated for IHC.
Tau proteins are microtubule-associated proteins transcribed from the MAPT gene. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. In Alzheimer's disease, the neuronal cytoskeleton in the brain is progressively disrupted and replaced by tangles of paired helical filaments (PHF) and straight filaments, mainly composed of hyperphosphorylated forms of TAU. Abnormal quantities of Tau protein in neurons and sometimes astrocytes are also seen in progressive supranuclear palsy. In immunohistochemistry of normal tissue, Tau has positive cytoplasmic staining in the central nervous system, renal tubules and in peripheral nerves, with some expression in other tissues including skeletal muscle, kidney and breast.
Tau proteins are microtubule-associated proteins transcribed from the MAPT gene. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. In Alzheimer's disease, the neuronal cytoskeleton in the brain is progressively disrupted and replaced by tangles of paired helical filaments (PHF) and straight filaments, mainly composed of hyperphosphorylated forms of TAU. Abnormal quantities of Tau protein in neurons and sometimes astrocytes are also seen in progressive supranuclear palsy. In immunohistochemistry of normal tissue, Tau has positive cytoplasmic staining in the central nervous system, renal tubules and in peripheral nerves, with some expression in other tissues including skeletal muscle, kidney and breast.
References
J Mol Biol. 2016 May 8;428(9 Pt A):1742-59, PMID: 26996940; PNAS. 2015 June. 112 (24) 7501-7506, DOI: 10.1073/pnas.1504081112; Acta Neuropathol. 1991;81(6):591-6, PMID: 1831952
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
78,928 Da
NCBI Official Full Name
microtubule-associated protein tau isoform 6
NCBI Official Synonym Full Names
microtubule-associated protein tau
NCBI Official Symbol
MAPT
NCBI Official Synonym Symbols
TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17
NCBI Protein Information
microtubule-associated protein tau; PHF-tau; paired helical filament-tau; neurofibrillary tangle protein; microtubule-associated protein tau, isoform 4; G protein beta1/gamma2 subunit-interacting factor 1
UniProt Protein Name
Microtubule-associated protein tau
UniProt Gene Name
MAPT
UniProt Synonym Gene Names
MAPTL; MTBT1; TAU; PHF-tau
UniProt Entry Name
TAU_HUMAN
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Product Notes
The MAPT mapt (Catalog #AAA163171) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAPT/Tau Rabbit anti-Human Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MAPT/Tau can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the MAPT mapt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAPT/Tau, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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