IHC (Immunohiostchemistry)
(MBTPS2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MBTPS2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit MBTPS2 Polyclonal Antibody | anti-MBTPS2 antibody
MBTPS2 Antibody (N-term)
Gene Names
MBTPS2; S2P; IFAP; KFSD; KFSDX; OLMSX; BRESEK
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MBTPS2, Antibody; MBTPS2 Antibody (N-term); Membrane-bound transcription factor site-2 protease; Endopeptidase S2P; Sterol regulatory element-binding proteins intramembrane protease; SREBPs intramembrane protease; MBTPS2; S2P; anti-MBTPS2 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MBTPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human MBTPS2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
15-44
Sequence Length
519
Applicable Applications for anti-MBTPS2 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(MBTPS2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MBTPS2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(MBTPS2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MBTPS2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(MBTPS2 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the MBTPS2 antibody detected the MBTPS2 protein (arrow).)
WB (Western Blot)
(MBTPS2 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the MBTPS2 antibody detected the MBTPS2 protein (arrow).)
Related Product Information for anti-MBTPS2 antibody
This gene encodes a intramembrane zinc metalloprotease,
which is essential in development. This protease functions in the
signal protein activation involved in sterol control of
transcription and the ER stress response. Mutations in this gene
have been associated with ichthyosis follicularis with atrichia and
photophobia (IFAP syndrome); IFAP syndrome has been quantitatively
linked to a reduction in cholesterol homeostasis and ER stress
response.
which is essential in development. This protease functions in the
signal protein activation involved in sterol control of
transcription and the ER stress response. Mutations in this gene
have been associated with ichthyosis follicularis with atrichia and
photophobia (IFAP syndrome); IFAP syndrome has been quantitatively
linked to a reduction in cholesterol homeostasis and ER stress
response.
Product Categories/Family for anti-MBTPS2 antibody
References
Ming, A., et al. Pediatr Dermatol 26(4):427-431(2009)
Oeffner, F., et al. Am. J. Hum. Genet. 84(4):459-467(2009)
Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)
Shen, J., et al. J. Biol. Chem. 279(41):43046-43051(2004)
Lee, K., et al. Genes Dev. 16(4):452-466(2002)
Oeffner, F., et al. Am. J. Hum. Genet. 84(4):459-467(2009)
Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)
Shen, J., et al. J. Biol. Chem. 279(41):43046-43051(2004)
Lee, K., et al. Genes Dev. 16(4):452-466(2002)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57444
NCBI Official Full Name
membrane-bound transcription factor site-2 protease
NCBI Official Synonym Full Names
membrane-bound transcription factor peptidase, site 2
NCBI Official Symbol
MBTPS2
NCBI Official Synonym Symbols
S2P; IFAP; KFSD; KFSDX; OLMSX; BRESEK
NCBI Protein Information
membrane-bound transcription factor site-2 protease
UniProt Protein Name
Membrane-bound transcription factor site-2 protease
UniProt Gene Name
MBTPS2
UniProt Synonym Gene Names
S2P; SREBPs intramembrane protease
UniProt Entry Name
MBTP2_HUMAN
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Product Notes
The MBTPS2 mbtps2 (Catalog #AAA288594) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 15-44. The MBTPS2 Antibody (N-term) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's MBTPS2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the MBTPS2 mbtps2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MBTPS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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