FCM/FACS (Flow Cytometry)
(MC2R Antibody (C-term) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Rabbit MC2R Polyclonal Antibody | anti-MC2R antibody
MC2R Antibody (C-term)
Gene Names
MC2R; ACTHR
Reactivity
Human (Predicted Reactivity: Mouse, Pig)
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MC2R, Antibody; MC2R Antibody (C-term); Adrenocorticotropic hormone receptor; ACTH receptor; ACTH-R; Adrenocorticotropin receptor; Melanocortin receptor 2; MC2-R; MC2R; ACTHR; anti-MC2R antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse, Pig)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MC2R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-288 amino acids from the C-terminal region of human MC2R.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
261-288
Sequence Length
297
Applicable Applications for anti-MC2R antibody
FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
FCM/FACS (Flow Cytometry)
(MC2R Antibody (C-term) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
FCM/FACS (Flow Cytometry)
(MC2R Antibody (C-term) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
IHC (Immunohiostchemistry)
(MC2R Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MC2R Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(MC2R Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MC2R Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(MC2R Antibody (C-term) western blot analysis in WiDr cell line lysates (15ug/lane).This demonstrates the MC2R antibody detected the MC2R protein (arrow).)
WB (Western Blot)
(MC2R Antibody (C-term) western blot analysis in WiDr cell line lysates (15ug/lane).This demonstrates the MC2R antibody detected the MC2R protein (arrow).)
Related Product Information for anti-MC2R antibody
MC2R encodes one member of the five-member G-protein
associated melanocortin receptor family. Melanocortins
(melanocyte-stimulating hormones and adrenocorticotropic hormone)
are peptides derived from pro-opiomelanocortin (POMC). MC2R is
selectively activated by adrenocorticotropic hormone, whereas the
other four melanocortin receptors recognize a variety of
melanocortin ligands.
associated melanocortin receptor family. Melanocortins
(melanocyte-stimulating hormones and adrenocorticotropic hormone)
are peptides derived from pro-opiomelanocortin (POMC). MC2R is
selectively activated by adrenocorticotropic hormone, whereas the
other four melanocortin receptors recognize a variety of
melanocortin ligands.
Product Categories/Family for anti-MC2R antibody
References
Holliday, K.L., et al. Ann. Rheum. Dis. 69(3):556-560(2010)
Ding, Y.X., et al. Pharmacogenet. Genomics 20(2):71-76(2010)
Roy, S., et al. Endocrinology 151(2):660-670(2010)
Ding, Y.X., et al. Pharmacogenet. Genomics 20(2):71-76(2010)
Roy, S., et al. Endocrinology 151(2):660-670(2010)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
33927
NCBI Official Full Name
adrenocorticotropic hormone receptor
NCBI Official Synonym Full Names
melanocortin 2 receptor (adrenocorticotropic hormone)
NCBI Official Symbol
MC2R
NCBI Official Synonym Symbols
ACTHR
NCBI Protein Information
adrenocorticotropic hormone receptor
UniProt Protein Name
Adrenocorticotropic hormone receptor
UniProt Gene Name
MC2R
UniProt Synonym Gene Names
ACTHR; ACTH receptor; ACTH-R; MC2-R
UniProt Entry Name
ACTHR_HUMAN
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Product Notes
The MC2R mc2r (Catalog #AAA283624) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 261-288. The MC2R Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse, Pig) and may cross-react with other species as described in the data sheet. AAA Biotech's MC2R can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the MC2R mc2r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MC2R, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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