IHC (Immunohistochemisry)
(MCA1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymphnode followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MCA1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit MCA1 Polyclonal Antibody | anti-AIMP1 antibody
MCA1 Antibody (C-term)
Gene Names
AIMP1; p43; HLD3; EMAP2; SCYE1; EMAPII
Reactivity
Human (Predicted Reactivity: Hamster, Mouse)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MCA1, Antibody; MCA1 Antibody (C-term); Aminoacyl tRNA synthase complex-interacting multifunctional protein 1; Multisynthase complex auxiliary component p43; Endothelial monocyte-activating polypeptide 2; EMAP-2; Endothelial monocyte-activating polypeptide II; EMAP-II; Small inducible cytokine subfamily E member 1; AIMP1; EMAP2; SCYE1; anti-AIMP1 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Hamster, Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MCA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-268 amino acids from the C-terminal region of human MCA1.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
242-268
Sequence Length
336
Applicable Applications for anti-AIMP1 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohistochemisry)
(MCA1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymphnode followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MCA1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohistochemisry)
(MCA1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymphnode followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MCA1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of MCA1(arrow) using rabbit polyclonal MCA1 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MCA1 gene (Lane 2) (Origene Technologies).)
WB (Western Blot)
(Western blot analysis of MCA1(arrow) using rabbit polyclonal MCA1 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MCA1 gene (Lane 2) (Origene Technologies).)
WB (Western Blot)
(Western blot analysis of MCA1 antibody (C-term) in 293 cell line lysates (35ug/lane). MCA1 (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of MCA1 antibody (C-term) in 293 cell line lysates (35ug/lane). MCA1 (arrow) was detected using the purified Pab.)
Related Product Information for anti-AIMP1 antibody
MCA1 is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells.
Product Categories/Family for anti-AIMP1 antibody
References
Awasthi,N., Lab. Invest. 89 (1), 38-46 (2009)
Sen,E., Clin Lung Cancer 9 (3), 166-170 (2008)
Sen,E., Clin Lung Cancer 9 (3), 166-170 (2008)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34353
NCBI Official Full Name
aminoacyl tRNA synthase complex-interacting multifunctional protein 1 isoform a
NCBI Official Synonym Full Names
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
NCBI Official Symbol
AIMP1
NCBI Official Synonym Symbols
p43; HLD3; EMAP2; SCYE1; EMAPII
NCBI Protein Information
aminoacyl tRNA synthase complex-interacting multifunctional protein 1
UniProt Protein Name
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1
UniProt Gene Name
AIMP1
UniProt Synonym Gene Names
EMAP2; SCYE1; EMAP-2; EMAP-II
UniProt Entry Name
AIMP1_HUMAN
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Product Notes
The AIMP1 aimp1 (Catalog #AAA289944) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 242-268. The MCA1 Antibody (C-term) reacts with Human (Predicted Reactivity: Hamster, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's MCA1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the AIMP1 aimp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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