IHC (Immunohiostchemistry)
(Immunohistochemistry of ME1 in mouse liver tissue with ME1 antibody at 5 μg/mL.)
Rabbit ME1 Polyclonal Antibody | anti-ME1 antibody
ME1 Antibody
Gene Names
ME1; MES; HUMNDME
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
ME1 antibody is affinity chromatography purified via peptide column.
Synonyms
ME1, Antibody; ME1 Antibody; ME1; MES; HUMNDME; NADP-dependent malic enzyme; Malic enzyme 1; NADP-ME; malic enzyme 1, NADP(+)-dependent, cytosolic; anti-ME1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
ME1 antibody is human, mouse and rat reactive. ME1 antibody is predicted not to cross-react with ME2.
Purity/Purification
ME1 antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
572
Applicable Applications for anti-ME1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
ME1 antibody was raised against a 16 amino acid peptide near the amino terminus of human ME1.
Buffer
ME1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
ME1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IHC (Immunohiostchemistry)
(Immunohistochemistry of ME1 in mouse liver tissue with ME1 antibody at 5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of ME1 in mouse liver tissue with ME1 antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of ME1 in 293 cell lysate with ME1 antibody at 1 μg/ml.)
WB (Western Blot)
(Western blot analysis of ME1 in 293 cell lysate with ME1 antibody at 1 μg/ml.)
Related Product Information for anti-ME1 antibody
ME1, also known as NADP-ME, MES or HUMNDME, may play an important role as a housekeeping protein within the cell (1). ME1 is a 572 amino acid cytoplasmic protein that belongs to the malic enzyme family (2). It is expressed ubiquitously with highest expression in liver and white adipose tissue. ME1 functions as an NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis (3). The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles (3,4). ME1 is regulated by both thyroid hormone levels and the amount of carbohydrates in the diet (5).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 63 kDa
Observed: 63 kDa
Observed: 63 kDa
NCBI Official Full Name
NADP-dependent malic enzyme
NCBI Official Synonym Full Names
malic enzyme 1, NADP(+)-dependent, cytosolic
NCBI Official Symbol
ME1
NCBI Official Synonym Symbols
MES; HUMNDME
NCBI Protein Information
NADP-dependent malic enzyme; NADP-ME; malate dehydrogenase; malic enzyme 1, soluble; Malic enzyme, cytoplasmic; pyruvic-malic carboxylase
UniProt Protein Name
NADP-dependent malic enzyme
UniProt Gene Name
ME1
UniProt Synonym Gene Names
NADP-ME
UniProt Entry Name
MAOX_HUMAN
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Product Notes
The ME1 me1 (Catalog #AAA40787) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ME1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ME1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ME1 me1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ME1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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