WB (Western Blot)
((2ug/ml) staining of Human Cerebellum (A) and Rat Brain (B) lysates (35 ug protein in RIPA buffer).Primary incubation was 1 hour. Detected by chemiluminescence.)
Rabbit Melanocortin receptor 4 Polyclonal Antibody | anti-MC4R antibody
Anti-Mouse Melanocortin receptor 4, Affinity Purified, (Polyclonal), (Rabbit IgG)
Reactivity
Mouse, Rat, Human
Applications
Immunohistochemistry, Western Blot, ELISA
Synonyms
Melanocortin receptor 4, Antibody; Anti-Mouse Melanocortin receptor 4, Affinity Purified, (Polyclonal), (Rabbit IgG); anti-MC4R antibody
Host
Rabbit
Reactivity
Mouse, Rat, Human
Clonality
Polyclonal
Isotype
IgG
Specificity
This antibody is specific for mouse, rat, and human MC4R.
Form/Format
Affinity Purified
Sequence Length
332
Applicable Applications for anti-MC4R antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Presentation
100 ug (MBS524440) or 20 ug (MBS524440-S) purified IgG buffered in PBS and 0.02% NaN3• (Purified from serum
via Affinity Chromatography). For maximum recovery of contents, spin down tube before use.
Immunogen
15 amino acid synthetic peptide located within the 1st extracellular domain of mouse MC4R.
Preparation and Storage
Store at + 4°C. For long term storage, aliquot and freeze unused portion at -20°C in volumes appropriate for single
usage. Avoid freeze/thaw cycles.
WB (Western Blot)
((2ug/ml) staining of Human Cerebellum (A) and Rat Brain (B) lysates (35 ug protein in RIPA buffer).Primary incubation was 1 hour. Detected by chemiluminescence.)
WB (Western Blot)
((2ug/ml) staining of Human Cerebellum (A) and Rat Brain (B) lysates (35 ug protein in RIPA buffer).Primary incubation was 1 hour. Detected by chemiluminescence.)
Related Product Information for anti-MC4R antibody
Melanocortin 4 receptor is a G-protein-coupled receptor from the melanocortin receptor family that binds amelanocyte stimulating hormon ~(a-MSH). These receptors transduce signals provided by a-MSH by coupling to the G-protein and activating adenyl ate cyclase). MC4R is located mainly in the hypothalamus in the brain and it is responsible for appetite and satiety regulation. It also plays a role in energy homeostasis and somatic growth. Mutations in MC4R have been associated with inherited obesity2.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36,943 Da
NCBI Official Full Name
melanocortin receptor 4
NCBI Official Synonym Full Names
melanocortin 4 receptor
NCBI Official Symbol
MC4R
NCBI Protein Information
melanocortin receptor 4
UniProt Protein Name
Melanocortin receptor 4
UniProt Gene Name
MC4R
UniProt Synonym Gene Names
MC4-R
UniProt Entry Name
MC4R_HUMAN
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Product Notes
The MC4R mc4r (Catalog #AAA74283) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse Melanocortin receptor 4, Affinity Purified, (Polyclonal), (Rabbit IgG) reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's Melanocortin receptor 4 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the MC4R mc4r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Melanocortin receptor 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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