IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human brain tissue using MER/SKY (Phospho-Tyr749/681) antibody (left)or the same antibody preincubated with blocking peptide (right).)
Rabbit anti-Human, Mouse MER/SKY Polyclonal Antibody | anti-MER/SKY antibody
MER/SKY (Phospho-Tyr749/681) Antibody
Gene Names
MERTK; MER; RP38; c-Eyk; c-mer; Tyro12
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Synonyms
MER/SKY, Antibody; MER/SKY (Phospho-Tyr749/681) Antibody; C-mer; MERK; MERTK; anti-MER/SKY antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of MER/SKY only when phosphorylated at tyrosine 749/681.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
999
Applicable Applications for anti-MER/SKY antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide-KLH
Immunogen Description
Peptide sequence around phosphorylation site of tyrosine 749/681(K-I-Y(p)-S-G) derived from Human MER/SKY.
Modification
Phospho-Tyr749/681
Target Name
MER/SKY
Purification
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Preparation and Storage
Store at -20 degree C/1 year
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human brain tissue using MER/SKY (Phospho-Tyr749/681) antibody (left)or the same antibody preincubated with blocking peptide (right).)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human brain tissue using MER/SKY (Phospho-Tyr749/681) antibody (left)or the same antibody preincubated with blocking peptide (right).)
WB (Western Blot)
(Western blot analysis of extracts from 3T3 cells treated with EGF using MER/SKY (Phospho-Tyr749/681) Antibody.The lane on the right is treated with the antigen-specific peptide.)
WB (Western Blot)
(Western blot analysis of extracts from 3T3 cells treated with EGF using MER/SKY (Phospho-Tyr749/681) Antibody.The lane on the right is treated with the antigen-specific peptide.)
Related Product Information for anti-MER/SKY antibody
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). Graham D.K., Cell Growth Differ. 5:647-657(1994).Gal A., Nat. Genet. 26:270-271(2000).Hillier L.W., Nature 434:724-731(2005).
Product Categories/Family for anti-MER/SKY antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
97kd
NCBI Official Full Name
tyrosine-protein kinase Mer
NCBI Official Synonym Full Names
MER proto-oncogene, tyrosine kinase
NCBI Official Symbol
MERTK
NCBI Official Synonym Symbols
MER; RP38; c-Eyk; c-mer; Tyro12
NCBI Protein Information
tyrosine-protein kinase Mer
UniProt Protein Name
Tyrosine-protein kinase Mer
UniProt Gene Name
MERTK
UniProt Synonym Gene Names
MER
UniProt Entry Name
MERTK_HUMAN
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Product Notes
The MER/SKY mertk (Catalog #AAA303839) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MER/SKY (Phospho-Tyr749/681) Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MER/SKY can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the MER/SKY mertk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MER/SKY, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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