IHC (Immunohiostchemistry)
(MGAT4C Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MGAT4C Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit MGAT4C Polyclonal Antibody | anti-MGAT4C antibody
MGAT4C Antibody (C-term)
Gene Names
MGAT4C; GNTIVH; HGNT-IV-H
Reactivity
Human (Predicted Reactivity: Monkey, Mouse, Pig)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
This antibody is purified through a protein A column, followed by peptide affinity purification.
Synonyms
MGAT4C, Antibody; MGAT4C Antibody (C-term); Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C; N-acetylglucosaminyltransferase IV homolog; hGnT-IV-H; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc; GlcNAc-T IVc; GnT-IVc; N-acetylglucosaminyltransferase IVc; UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc; MGAT4C; anti-MGAT4C antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Monkey, Mouse, Pig)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MGAT4C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-332 amino acids from the C-terminal region of human MGAT4C.
Purity/Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Sequence Positions
303-332
Sequence Length
478
Applicable Applications for anti-MGAT4C antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Function
Glycosyltransferase that participates in the transfer of N- acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essntial for the production of tri- and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity)
Cellular Location
Golgi apparatus membrane; Single- pass type II membrane protein
Tissue Location
Expressed in heart, adrenal gland, testis, liver, brain and fetal brain. Not expressed in pancreas
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(MGAT4C Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MGAT4C Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(MGAT4C Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MGAT4C Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(MGAT4C Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MGAT4C antibody detected the MGAT4C protein (arrow).)
WB (Western Blot)
(MGAT4C Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MGAT4C antibody detected the MGAT4C protein (arrow).)
Related Product Information for anti-MGAT4C antibody
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri-and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity).
Product Categories/Family for anti-MGAT4C antibody
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Furukawa, T., et al. J. Hum. Genet. 44(6):397-401(1999)
Thomas, B.A. Br. J. Dermatol. 80 (6), 413 (1968) :
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Furukawa, T., et al. J. Hum. Genet. 44(6):397-401(1999)
Thomas, B.A. Br. J. Dermatol. 80 (6), 413 (1968) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56061
NCBI Official Full Name
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C
NCBI Official Synonym Full Names
MGAT4 family, member C
NCBI Official Symbol
MGAT4C
NCBI Official Synonym Symbols
GNTIVH; HGNT-IV-H
NCBI Protein Information
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C
UniProt Protein Name
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C
UniProt Gene Name
MGAT4C
UniProt Synonym Gene Names
hGnT-IV-H; GlcNAc-T IVc; GnT-IVc; N-acetylglucosaminyltransferase IVc
UniProt Entry Name
MGT4C_HUMAN
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Product Notes
The MGAT4C mgat4c (Catalog #AAA289155) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 303-332. The MGAT4C Antibody (C-term) reacts with Human (Predicted Reactivity: Monkey, Mouse, Pig) and may cross-react with other species as described in the data sheet. AAA Biotech's MGAT4C can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the MGAT4C mgat4c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MGAT4C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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