IF (Immunofluorescence)
(Immunofluorescence of Mimitin in Raji cells with Mimitin antibody at 20 ug/mL.)
Rabbit anti-Human Mimitin Polyclonal Antibody | anti-NDUFAF2 antibody
Mimitin Antibody
Gene Names
NDUFAF2; MMTN; B17.2L; mimitin; NDUFA12L
Reactivity
Human
Applications
Immunofluorescence, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
Mimitin, Antibody; Mimitin Antibody; NADH dehydroxygenase (ubiquinone) 1 alpha subcomplex, assembly factor 2, NDUFAF2, NDUFA12L, MMTN; anti-NDUFAF2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
169
Applicable Applications for anti-NDUFAF2 antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 14 amino acid peptide from near the carboxy terminus of human Mimitin.
Target Name
Mimitin
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of Mimitin in Raji cells with Mimitin antibody at 20 ug/mL.)
IF (Immunofluorescence)
(Immunofluorescence of Mimitin in Raji cells with Mimitin antibody at 20 ug/mL.)
WB (Western Blot)
(Western blot analysis of Mimitin in Raji cell lysate with Mimitin antibody at (A) 1 and (B) 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of Mimitin in Raji cell lysate with Mimitin antibody at (A) 1 and (B) 2 ug/mL.)
Related Product Information for anti-NDUFAF2 antibody
Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80% of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-kB-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis. Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I.
Product Categories/Family for anti-NDUFAF2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19,856 Da
NCBI Official Full Name
mimitin, mitochondrial
NCBI Official Synonym Full Names
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
NCBI Official Symbol
NDUFAF2
NCBI Official Synonym Symbols
MMTN; B17.2L; mimitin; NDUFA12L
NCBI Protein Information
mimitin, mitochondrial
UniProt Protein Name
Mimitin, mitochondrial
UniProt Gene Name
NDUFAF2
UniProt Synonym Gene Names
NDUFA12L; B17.2L; MMTN
UniProt Entry Name
MIMIT_HUMAN
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Product Notes
The NDUFAF2 ndufaf2 (Catalog #AAA308311) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mimitin Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Mimitin can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the NDUFAF2 ndufaf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mimitin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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