IHC (Immunohiostchemistry)
(MLPH Antibdy (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MLPH Antibdy (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human MLPH Polyclonal Antibody | anti-MLPH antibody
MLPH Antibody (C-term)
Gene Names
MLPH; SLAC2-A
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MLPH, Antibody; MLPH Antibody (C-term); Melanophilin; Exophilin-3; Slp homolog lacking C2 domains a; SlaC2-a; Synaptotagmin-like protein 2a; MLPH; SLAC2A; anti-MLPH antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MLPH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-569 amino acids from the C-terminal region of human MLPH.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
541-569
Sequence Length
572
Applicable Applications for anti-MLPH antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(MLPH Antibdy (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MLPH Antibdy (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(MLPH Antibdy (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MLPH Antibdy (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(MLPH Antibody (C-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the MLPH antibody detected the MLPH protein (arrow).)
WB (Western Blot)
(MLPH Antibody (C-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the MLPH antibody detected the MLPH protein (arrow).)
Related Product Information for anti-MLPH antibody
This gene encodes a member of the exophilin subfamily of
Rab effector proteins. The protein forms a ternary complex with the
small Ras-related GTPase Rab27A in its GTP-bound form and the motor
protein myosin Va. A similar protein complex in mouse functions to
tether pigment-producing organelles called melanosomes to the actin
cytoskeleton in melanocytes, and is required for visible
pigmentation in the hair and skin. A mutation in this gene results
in Griscelli syndrome type 3, which is characterized by a
silver-gray hair color and abnormal pigment distribution in the
hair shaft. Several alternatively spliced transcript variants of
this gene have been described, but the full-length nature of some
of these variants has not been determined.
Rab effector proteins. The protein forms a ternary complex with the
small Ras-related GTPase Rab27A in its GTP-bound form and the motor
protein myosin Va. A similar protein complex in mouse functions to
tether pigment-producing organelles called melanosomes to the actin
cytoskeleton in melanocytes, and is required for visible
pigmentation in the hair and skin. A mutation in this gene results
in Griscelli syndrome type 3, which is characterized by a
silver-gray hair color and abnormal pigment distribution in the
hair shaft. Several alternatively spliced transcript variants of
this gene have been described, but the full-length nature of some
of these variants has not been determined.
Product Categories/Family for anti-MLPH antibody
References
Park, J.W., et al. J. Med. Genet. 43(7):598-608(2006)
Seabra, M.C., et al. Traffic 5(6):393-399(2004)
Fukuda, M., et al. J. Cell. Sci. 117 (PT 4), 583-591 (2004) :
Lukusa, T., et al. Genet. Couns. 15(3):293-301(2004)
Menasche, G., et al. J. Clin. Invest. 112(3):450-456(2003)
Seabra, M.C., et al. Traffic 5(6):393-399(2004)
Fukuda, M., et al. J. Cell. Sci. 117 (PT 4), 583-591 (2004) :
Lukusa, T., et al. Genet. Couns. 15(3):293-301(2004)
Menasche, G., et al. J. Clin. Invest. 112(3):450-456(2003)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
65949
NCBI Official Full Name
melanophilin isoform 2
NCBI Official Synonym Full Names
melanophilin
NCBI Official Symbol
MLPH
NCBI Official Synonym Symbols
SLAC2-A
NCBI Protein Information
melanophilin
UniProt Protein Name
Melanophilin
UniProt Gene Name
MLPH
UniProt Synonym Gene Names
SLAC2A; SlaC2-a
UniProt Entry Name
MELPH_HUMAN
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Product Notes
The MLPH mlph (Catalog #AAA288269) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 541-569. The MLPH Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MLPH can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the MLPH mlph for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MLPH, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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