IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human cervical cancer using MMP-1 Polyclonal Antibody at dilution of 1:1200)
Rabbit anti-Human MMP-1 Polyclonal Antibody | anti-MMP-1 antibody
MMP-1 Polyclonal Antibody
Gene Names
Mmp1a; Mcola; Mcol-A
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
MMP-1, Antibody; MMP-1 Polyclonal Antibody; CLGmatrix metalloprotease 1; CLGN; EC 3.4.24; EC 3.4.24.7; Fibroblast collagenase; interstitial collagenase; matrix metallopeptidase 1 (interstitial collagenase); matrix metalloproteinase 1 (interstitial collagenase); Matrix metalloproteinase-1; MMP1; MMP-1; anti-MMP-1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-MMP-1 antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant Mouse MMP-1 protein expressed by E coli
Preparation and Storage
Store at -20 degree C Valid for 12 months. Avoid freeze/thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human cervical cancer using MMP-1 Polyclonal Antibody at dilution of 1:1200)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human cervical cancer using MMP-1 Polyclonal Antibody at dilution of 1:1200)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human lung cancer using MMP-1 Polyclonal Antibody at dilution of 1:1200)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human lung cancer using MMP-1 Polyclonal Antibody at dilution of 1:1200)
Related Product Information for anti-MMP-1 antibody
Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-1 (interstitial collagenase), can degrade a broad range of substrates including types I, II, III, VII, VIII, and X collagens as well as casein, gelatin, alpha ?1 antitrypsin, myelin basic protein, L-Selectin, pro-TNF, IL-1 beta, IGF-BP3, IGF-BP5, pro MMP-2 and pro MMP-9. A significant role of MMP-1 is the degradation of fibrillar collagens in extracellular matrix remodeling, characterized by the cleavage of the interstitial collagen triple helix into ?, ? fragments. However, as the list of substrates above illustrates, the role of MMP-1 is more diverse than originally envisaged, and may involve enzyme cascades, cytokine regulation and cell surface molecule modulation. MMP-1 is expressed by fibroblasts, keratinocytes, endothelial cells, monocytes and macrophages. Structurally, MMP-1 may be divided into several distinct domains; a pro-domain which is cleaved upon activation; a catalytic domain containing the zinc binding site; a short hinge region and a carboxyl terminal (hemopexin-like) domain.
Product Categories/Family for anti-MMP-1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
53,488 Da
NCBI Official Full Name
interstitial collagenase A
NCBI Official Synonym Full Names
matrix metallopeptidase 1a (interstitial collagenase)
NCBI Official Symbol
Mmp1a
NCBI Official Synonym Symbols
Mcola; Mcol-A
NCBI Protein Information
interstitial collagenase A
UniProt Protein Name
Interstitial collagenase A
UniProt Gene Name
Mmp1a
UniProt Synonym Gene Names
McolA; MMP-1a
UniProt Entry Name
MMP1A_MOUSE
Similar Products
Product Notes
The MMP-1 mmp1a (Catalog #AAA179802) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MMP-1 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MMP-1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the MMP-1 mmp1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MMP-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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