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WB (Western Blot)
(Western blot analysis of extracts from HepG2 cells (Lane 2) and HeLa cells (Lane 3), using MMP-11 antiobdy. The lane on the left is treated with systhesized peptide.)
Rabbit MMP-11 Polyclonal Antibody | anti-MMP-11 antibody
MMP-11 Antibody
Gene Names
MCM5; CDC46; P1-CDC46
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
MMP-11, Antibody; MMP-11 Antibody; CDC46; DNA replication licensing factor MMP-11; minichromosome maintenance deficient protein 5; anti-MMP-11 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total MMP-11 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
734
Applicable Applications for anti-MMP-11 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from human MMP-11 antibody.
Target Name
MMP-11
Preparation and Storage
Store at -20 degree C
WB (Western Blot)
(Western blot analysis of extracts from HepG2 cells (Lane 2) and HeLa cells (Lane 3), using MMP-11 antiobdy. The lane on the left is treated with systhesized peptide.)
WB (Western Blot)
(Western blot analysis of extracts from HepG2 cells (Lane 2) and HeLa cells (Lane 3), using MMP-11 antiobdy. The lane on the left is treated with systhesized peptide.)
WB (Western Blot)
(Western blot analysis of extracts from A549 cells, using MMP-11 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from A549 cells, using MMP-11 antibody.)
IF (Immunofluorescence)
(Immunofluorescence analysis of A549 cells, using MMP-11 antibody.)
IF (Immunofluorescence)
(Immunofluorescence analysis of A549 cells, using MMP-11 antibody.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MMP-11 antibody.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MMP-11 antibody.)
Related Product Information for anti-MMP-11 antibody
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity By similarity. Interacts with MCMBP.Robert A. Sclafani, Genetics, May 2002; 161: 47. Marylynn Snyder, PNAS, Oct 2005; 102: 14539 - 14544. Christopher J. DaFonseca, PNAS, Mar 2001; 98: 3034. Cathleen M. Lake, Genetics, Jun 2007; 10.1534.
Product Categories/Family for anti-MMP-11 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
82,286 Da
NCBI Official Full Name
DNA replication licensing factor MCM5
NCBI Official Synonym Full Names
minichromosome maintenance complex component 5
NCBI Official Symbol
MCM5
NCBI Official Synonym Symbols
CDC46; P1-CDC46
NCBI Protein Information
DNA replication licensing factor MCM5
UniProt Protein Name
DNA replication licensing factor MCM5
UniProt Gene Name
MCM5
UniProt Synonym Gene Names
CDC46
UniProt Entry Name
MCM5_HUMAN
Similar Products
Product Notes
The MMP-11 mcm5 (Catalog #AAA303987) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MMP-11 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MMP-11 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the MMP-11 mcm5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MMP-11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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