IHC (Immunohiostchemistry)
(MMP15 Antibody (N-term) (AAA285939)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MMP15 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human MMP15 Polyclonal Antibody | anti-MMP15 antibody
MMP15 Antibody (N-term)
Gene Names
MMP15; MTMMP2; SMCP-2; MT2-MMP
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MMP15, Antibody; MMP15 Antibody (N-term); Matrix metalloproteinase-15; MMP-15; 3424-; Membrane-type matrix metalloproteinase 2; MT-MMP 2; MTMMP2; Membrane-type-2 matrix metalloproteinase; MT2-MMP; MT2MMP; SMCP-2; MMP15; anti-MMP15 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MMP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-196 amino acids from the N-terminal region of human MMP15.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
168-196
Sequence Length
669
Applicable Applications for anti-MMP15 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(MMP15 Antibody (N-term) (AAA285939)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MMP15 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(MMP15 Antibody (N-term) (AAA285939)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MMP15 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(MMP15 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MMP15 antibody detected the MMP15 protein (arrow).)
WB (Western Blot)
(MMP15 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MMP15 antibody detected the MMP15 protein (arrow).)
Related Product Information for anti-MMP15 antibody
Proteins of the matrix metalloproteinase (MMP) family are
involved in the breakdown of extracellular matrix in normal
physiological processes, such as embryonic development,
reproduction, and tissue remodeling, as well as in disease
processes, such as arthritis and metastasis. Most MMP's are
secreted as inactive proproteins which are activated when cleaved
by extracellular proteinases. However, the protein encoded by this
gene is a member of the membrane-type MMP (MT-MMP) subfamily; each
member of this subfamily contains a potential transmembrane domain
suggesting that these proteins are expressed at the cell surface
rather than secreted.
involved in the breakdown of extracellular matrix in normal
physiological processes, such as embryonic development,
reproduction, and tissue remodeling, as well as in disease
processes, such as arthritis and metastasis. Most MMP's are
secreted as inactive proproteins which are activated when cleaved
by extracellular proteinases. However, the protein encoded by this
gene is a member of the membrane-type MMP (MT-MMP) subfamily; each
member of this subfamily contains a potential transmembrane domain
suggesting that these proteins are expressed at the cell surface
rather than secreted.
Product Categories/Family for anti-MMP15 antibody
References
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Nalpas, B., et al. Gut 59(8):1120-1126(2010)
Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :
Mohammad, M.A., et al. Int. J. Biol. Markers 25(2):69-74(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Nalpas, B., et al. Gut 59(8):1120-1126(2010)
Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :
Mohammad, M.A., et al. Int. J. Biol. Markers 25(2):69-74(2010)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
75807
NCBI Official Full Name
matrix metalloproteinase-15 preproprotein
NCBI Official Synonym Full Names
matrix metallopeptidase 15 (membrane-inserted)
NCBI Official Symbol
MMP15
NCBI Official Synonym Symbols
MTMMP2; SMCP-2; MT2-MMP
NCBI Protein Information
matrix metalloproteinase-15
UniProt Protein Name
Matrix metalloproteinase-15
UniProt Gene Name
MMP15
UniProt Synonym Gene Names
MMP-15; MT-MMP 2; MTMMP2; MT2-MMP; MT2MMP
UniProt Entry Name
MMP15_HUMAN
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Product Notes
The MMP15 mmp15 (Catalog #AAA285939) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 168-196. The MMP15 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MMP15 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the MMP15 mmp15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MMP15, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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