IF (Immunofluorescence)
(Immunofluorescence of MPYS in A-20 cells with MPYS antibody at 20 ug/mL.)
Rabbit anti-Human, Mouse MPYS Polyclonal Antibody | anti-TMEM173 antibody
MPYS Antibody
Gene Names
TMEM173; ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING
Reactivity
Human, Mouse
Applications
Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
Purity
MPYS Antibody is affinity chromatography purified via peptide column.
Synonyms
MPYS, Antibody; MPYS Antibody; MPYS; ERIS; MITA; NET23; STING; Stimulator of interferon genes protein; Endoplasmic reticulum interferon stimulator; hSTING; transmembrane protein 173; anti-TMEM173 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
MPYS Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
379
Applicable Applications for anti-TMEM173 antibody
IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
MPYS antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MPYS.
Buffer
MPYS Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
Antibody can be stored at 4 degree C up to one year. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of MPYS in A-20 cells with MPYS antibody at 20 ug/mL.)
IF (Immunofluorescence)
(Immunofluorescence of MPYS in A-20 cells with MPYS antibody at 20 ug/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of MPYS in A-20 cells with MPYS antibody at 5 μg/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of MPYS in A-20 cells with MPYS antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of MPYS in (A) K562 and (B) Jurkat cell lysate with MPYS antibody at 1 μg/mL.)
WB (Western Blot)
(Western blot analysis of MPYS in (A) K562 and (B) Jurkat cell lysate with MPYS antibody at 1 μg/mL.)
Related Product Information for anti-TMEM173 antibody
MPYS Antibody: MPYS is a recently identified plasma membrane tetraspanner that is associated with major histocompatibility complex class II (MHC-II) and mediates its transduction of apoptotic signals. It has also been found to be associated with VISA, a mitochondrial protein that acts as an adaptor in virus-triggered signaling. MPYS also interacts with IRF3 and recruits the kinase TBK1 to the VISA-associated complex, acting as a critical mediator of virus-triggered IRF3 activation and interferon (IFN) expression. It is thought that the binding of nucleic acid to the innate immune protein RIG-I causes complex formation between RIG-I, VISA, and MPYS. This complex then recruits TBK1 to phosphorylate IRF3 which then directly activates IFN transcription. At least three isoforms of MPYS are known to exist.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 31; 42 kDa
Observed: 37 kDa
Observed: 37 kDa
NCBI Official Full Name
stimulator of interferon genes protein isoform 1
NCBI Official Synonym Full Names
transmembrane protein 173
NCBI Official Symbol
TMEM173
NCBI Official Synonym Symbols
ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING
NCBI Protein Information
stimulator of interferon genes protein; endoplasmic reticulum IFN stimulator; mitochondrial mediator of IRF3 activation; endoplasmic reticulum interferon stimulator; N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner
UniProt Protein Name
Stimulator of interferon genes protein
UniProt Gene Name
TMEM173
UniProt Synonym Gene Names
ERIS; MITA; STING; hSTING; ERIS; hMITA
UniProt Entry Name
STING_HUMAN
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Product Notes
The TMEM173 tmem173 (Catalog #AAA39572) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MPYS Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MPYS can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the TMEM173 tmem173 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MPYS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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