IF (Immunofluorescence)
(Immunofluorescence analysis of HepG2 cells, using MRC2 antibody.)
Rabbit MRC2 Polyclonal Antibody | anti-MRC2 antibody
MRC2 Antibody
Gene Names
MRC2; CD280; UPARAP; CLEC13E; ENDO180
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
MRC2, Antibody; MRC2 Antibody; Macrophage mannose receptor 2 [Precursor]; Urokinase receptor-associated protein; Endocytic receptor 180; CD280 antigen; MRC2; anti-MRC2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total MRC2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
1479
Applicable Applications for anti-MRC2 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human MRC2.
Target Name
MRC2
Preparation and Storage
Store at -20 degree C
IF (Immunofluorescence)
(Immunofluorescence analysis of HepG2 cells, using MRC2 antibody.)
IF (Immunofluorescence)
(Immunofluorescence analysis of HepG2 cells, using MRC2 antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using MRC2 antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using MRC2 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from 293 cells, using MRC2 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from 293 cells, using MRC2 antibody.)
Related Product Information for anti-MRC2 antibody
May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).Behrendt N., J. Biol. Chem. 275:1993-2002(2000).Sheikh H., J. Cell Sci. 113:1021-1032(2000).Howard M.J., J. Biol. Chem. 277:32320-32331(2002).
Product Categories/Family for anti-MRC2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
166,674 Da
NCBI Official Full Name
C-type mannose receptor 2
NCBI Official Synonym Full Names
mannose receptor, C type 2
NCBI Official Symbol
MRC2
NCBI Official Synonym Symbols
CD280; UPARAP; CLEC13E; ENDO180
NCBI Protein Information
C-type mannose receptor 2
UniProt Protein Name
C-type mannose receptor 2
UniProt Gene Name
MRC2
UniProt Synonym Gene Names
CLEC13E; ENDO180; KIAA0709; UPARAP; UPAR-associated protein; Urokinase receptor-associated protein
UniProt Entry Name
MRC2_HUMAN
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Product Notes
The MRC2 mrc2 (Catalog #AAA307472) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MRC2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MRC2 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the MRC2 mrc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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