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product-image-AAA328040_IHC11.jpg IHC (Immunohistochemisry) (AAA328040 at 1/100 staining Mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)

Rabbit MRP6 Polyclonal Antibody | anti-MRP6 antibody

MRP6 Antibody

Gene Names
ABCC6; ARA; PXE; MLP1; MRP6; PXE1; URG7; ABC34; GACI2; MOATE; MOAT-E; EST349056
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
MRP6, Antibody; MRP6 Antibody; ABC34; Abcc6; Anthracycline resistance-associated protein; ARA; ATP binding cassette sub family C (CFTR/MRP) member 6; ATP binding cassette sub family C member 6; ATP-binding cassette sub-family C member 6; EST349056; GACI2; MLP1; MOAT E; MOAT-E; MOATE; MRP 6; MRP6; MRP6_HUMAN; Multi-specific organic anion transporter E; Multidrug resistance associated protein 6; Multidrug resistance-associated protein 6; URG7 protein; multispecific organic anion transporter E; PXE; PXE1; URG7; anti-MRP6 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
MRP6 antibody detects endogenous levels of total MRP6
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
99
Applicable Applications for anti-MRP6 antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthesized peptide derived from human MRP6
Subcellular Location
Membrane. Localized to the basolateral membrane.
Tissue Specificity
Expressed in kidney and liver. Very low expression in other tissues.
Predicted Cross Reactivity
Bovine, Horse, Sheep
Similarity
Bovine (80%), Horse (80%), Sheep (80%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

IHC (Immunohistochemisry)

(AAA328040 at 1/100 staining Mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)

product-image-AAA328040_IHC11.jpg IHC (Immunohistochemisry) (AAA328040 at 1/100 staining Mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)

WB (Western Blot)

(Western blot analysis of extracts from mouse muscle, using MRP6 Antibody.)

product-image-AAA328040_WB13.jpg WB (Western Blot) (Western blot analysis of extracts from mouse muscle, using MRP6 Antibody.)

WB (Western Blot)

(Western blot analysis of MRP6 using Jurkat whole cell lysates)

product-image-AAA328040_WB15.jpg WB (Western Blot) (Western blot analysis of MRP6 using Jurkat whole cell lysates)
Related Product Information for anti-MRP6 antibody
Function: Isoform 1: May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Transports glutathione conjugates as leukotriene-c4 (LTC4) and N-ethylmaleimide S-glutathione (NEM-GS).
Similarity: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
368
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 165 kDa
Predicted: 165 kDa
NCBI Official Full Name
URG7 protein isoform 2
NCBI Official Synonym Full Names
ATP binding cassette subfamily C member 6
NCBI Official Symbol
ABCC6
NCBI Official Synonym Symbols
ARA; PXE; MLP1; MRP6; PXE1; URG7; ABC34; GACI2; MOATE; MOAT-E; EST349056
NCBI Protein Information
multidrug resistance-associated protein 6; URG7 protein
UniProt Protein Name
Multidrug resistance-associated protein 6
UniProt Gene Name
ABCC6
UniProt Synonym Gene Names
ARA; MRP6; MOAT-E

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Product Notes

The MRP6 abcc6 (Catalog #AAA328040) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MRP6 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MRP6 can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the MRP6 abcc6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRP6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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