IHC (Immunohistochemisry)
(MUTED Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MUTED Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit MUTED Polyclonal Antibody | anti-BLOC1S5 antibody
MUTED Antibody (Center)
Gene Names
BLOC1S5; MU; BLOS5; MUTED
Reactivity
Human, mouse (Predicted Reactivity: Pig)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MUTED, Antibody; MUTED Antibody (Center); Biogenesis of lysosome-related organelles complex 1 subunit 5; BLOC-1 subunit 5; Protein Muted homolog; BLOC1S5; MUTED; anti-BLOC1S5 antibody
Host
Rabbit
Reactivity
Human, mouse (Predicted Reactivity: Pig)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MUTED antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the Central region of human MUTED.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
40-68
Sequence Length
123
Applicable Applications for anti-BLOC1S5 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohistochemisry)
(MUTED Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MUTED Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohistochemisry)
(MUTED Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MUTED Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(MUTED Antibody (Center) western blot analysis in mouse bladder tissue lysates (15ug/lane).This demonstrates the MUTED antibody detected MUTED protein (arrow).)
WB (Western Blot)
(MUTED Antibody (Center) western blot analysis in mouse bladder tissue lysates (15ug/lane).This demonstrates the MUTED antibody detected MUTED protein (arrow).)
WB (Western Blot)
(MUTED Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (15ug/lane).This demonstrates the MUTED antibody detected MUTED protein (arrow).)
WB (Western Blot)
(MUTED Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (15ug/lane).This demonstrates the MUTED antibody detected MUTED protein (arrow).)
Related Product Information for anti-BLOC1S5 antibody
This gene encodes a component of BLOC-1 (biogenesis of
lysosome-related organelles complex 1). Components of this complex
are involved in the biogenesis of organelles such as melanosomes
and platelet-dense granules. A mouse model for Hermansky-Pudlak
Syndrome is mutated in the murine version of this gene. Alternative
splicing results in multiple transcript variants. Read-through
transcription exists between this gene and the upstream EEF1E1
(eukaryotic translation elongation factor 1 epsilon 1) gene, as
well as with the downstream TXNDC5 (thioredoxin domain containing
5) gene.
lysosome-related organelles complex 1). Components of this complex
are involved in the biogenesis of organelles such as melanosomes
and platelet-dense granules. A mouse model for Hermansky-Pudlak
Syndrome is mutated in the murine version of this gene. Alternative
splicing results in multiple transcript variants. Read-through
transcription exists between this gene and the upstream EEF1E1
(eukaryotic translation elongation factor 1 epsilon 1) gene, as
well as with the downstream TXNDC5 (thioredoxin domain containing
5) gene.
Product Categories/Family for anti-BLOC1S5 antibody
References
Morris, D.W., et al. Biol. Psychiatry 63(1):24-31(2008)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Starcevic, M., et al. J. Biol. Chem. 279(27):28393-28401(2004)
Li, W., et al. Nat. Genet. 35(1):84-89(2003)
Ciciotte, S.L., et al. Blood 101(11):4402-4407(2003)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Starcevic, M., et al. J. Biol. Chem. 279(27):28393-28401(2004)
Li, W., et al. Nat. Genet. 35(1):84-89(2003)
Ciciotte, S.L., et al. Blood 101(11):4402-4407(2003)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21609
NCBI Official Full Name
biogenesis of lysosome-related organelles complex 1 subunit 5 isoform 2
NCBI Official Synonym Full Names
biogenesis of lysosomal organelles complex-1, subunit 5, muted
NCBI Official Symbol
BLOC1S5
NCBI Official Synonym Symbols
MU; BLOS5; MUTED
NCBI Protein Information
biogenesis of lysosome-related organelles complex 1 subunit 5
UniProt Protein Name
Biogenesis of lysosome-related organelles complex 1 subunit 5
UniProt Gene Name
BLOC1S5
UniProt Synonym Gene Names
MUTED; BLOC-1 subunit 5
UniProt Entry Name
BL1S5_HUMAN
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Product Notes
The BLOC1S5 bloc1s5 (Catalog #AAA284338) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 40-68. The MUTED Antibody (Center) reacts with Human, mouse (Predicted Reactivity: Pig) and may cross-react with other species as described in the data sheet. AAA Biotech's MUTED can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the BLOC1S5 bloc1s5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MUTED, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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