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product-image-AAA291001_FCM11.jpg FCM/FACS (Flow Cytometry) (FC: 1:10~50MVD Antibody (Center) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Rabbit anti-Human MVD Polyclonal Antibody | anti-MVD antibody

MVD Antibody (Center) Purified Rabbit Polyclonal Antibody (Pab)

Gene Names
MVD; MPD; MDDase; FP17780
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Flow Cytometry, Functional Assay, Western Blot
Purity
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Synonyms
MVD, Antibody; MVD Antibody (Center) Purified Rabbit Polyclonal Antibody (Pab); Diphosphomevalonate decarboxylase; Mevalonate (diphospho)decarboxylase; MDDase; Mevalonate pyrophosphate decarboxylase; MVD; MPD; anti-MVD antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Clone Number
RB18656
Specificity
This MVD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-193 amino acids from the Central region of human MVD.
Purity/Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Applicable Applications for anti-MVD antibody
ELISA, IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry), WB (Western Blot)
Antigen Source
Human
Antigen Type
Synthetic Peptide
Antigen Region
164-193
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

FCM/FACS (Flow Cytometry)

(FC: 1:10~50MVD Antibody (Center) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

product-image-AAA291001_FCM11.jpg FCM/FACS (Flow Cytometry) (FC: 1:10~50MVD Antibody (Center) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

IHC (Immunohiostchemistry)

(IHC-P: 1:50-100Formalin-fixed and paraffin-embedded human Skeletal muscle reacted with MVD Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

product-image-AAA291001_IHC13.jpg IHC (Immunohiostchemistry) (IHC-P: 1:50-100Formalin-fixed and paraffin-embedded human Skeletal muscle reacted with MVD Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

WB (Western Blot)

(WB: 1:1000Western blot analysis of MVD Antibody (Center) in HL60 cell line lysates (35ug/lane). MVD (arrow) was detected using the purified Pab.)

product-image-AAA291001_WB15.jpg WB (Western Blot) (WB: 1:1000Western blot analysis of MVD Antibody (Center) in HL60 cell line lysates (35ug/lane). MVD (arrow) was detected using the purified Pab.)
Related Product Information for anti-MVD antibody
The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP.
Product Categories/Family for anti-MVD antibody
References
Voynova,N.E., Arch. Biochem. Biophys. 480 (1), 58-67 (2008)Hogenboom,S., Mol. Genet. Metab. 81 (3), 216-224 (2004)Wadhwa,R., Biochem. Biophys. Res. Commun. 302 (4), 735-742 (2003)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
43,405 Da
NCBI Official Full Name
diphosphomevalonate decarboxylase
NCBI Official Synonym Full Names
mevalonate (diphospho) decarboxylase
NCBI Official Symbol
MVD
NCBI Official Synonym Symbols
MPD; MDDase; FP17780
NCBI Protein Information
diphosphomevalonate decarboxylase; mevalonate pyrophosphate decarboxylase
UniProt Protein Name
Diphosphomevalonate decarboxylase
UniProt Gene Name
MVD
UniProt Synonym Gene Names
MPD; MDDase
UniProt Entry Name
MVD1_HUMAN

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Product Notes

The MVD mvd (Catalog #AAA291001) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MVD Antibody (Center) Purified Rabbit Polyclonal Antibody (Pab) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MVD can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry), WB (Western Blot). Researchers should empirically determine the suitability of the MVD mvd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MVD, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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