Rabbit anti-Human Myc Polyclonal Antibody | anti-Myc antibody

Myc (Ab-358) Antibody

Cat. Num. AAA304898

• Gene Names: MYC; MRTL; MYCC; c-Myc; bHLHe39
• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot
• Purity: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
• Synonyms: Myc, Antibody; Myc (Ab-358) Antibody; c-myc; anti-Myc antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous level of total Myc protein.
• Purity/Purification: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
• Form/Format: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 454

• Applicable Applications for anti-Myc antibody: IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen Type: Peptide-KLH
• Immunogen Description: Peptide sequence around aa.356~360 (R-R-T-H-N) derived from Human Myc.
• Target Name: Myc
• Preparation and Storage: Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Myc(Ab-358) Antibody (left) or the same antibody preincubated with blocking peptide(right).)

WB (Western Blot)

(Western blot analysis of extracts from HL60, MCF and K562 cells using Myc(Ab-358) Antibody.)

Related Product Information for anti-Myc antibody

Myc proto-oncogene encodes nuclear DNA-binding phosphoproteins that are involved in the regulation of gene expression and DNA replication during cell growth and differentiation. Myc encodes a protein of 65 kDa which is expressed in almost all normal and transformed cells. The expression correlates with the proliferation state of the cells. Transcription is repressed in quiescent or terminally differentiated cells. Expression of Myc is generally induced after mitogenic stimulation of cells or serum induction. Myc therefore is an important positive regulator of cell growth and proliferation. Myc has been demonstrated also to be a potent inducer of apoptosis when expressed in the absence of serum or growth factors. Apoptosis may serve also as a protective mechanism to prevent tumorigenicity elicited by deregulated Myc expression. Sequences of the Myc oncogene have been highly conserved throughout evolution, from Drosophila to vertebrates

Product Categories/Family for anti-Myc antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 71774083
• NCBI GeneID: 4609
• NCBI Accession #: NP_002458.2
• NCBI GenBank Nucleotide #: NM_002467.4
• UniProt Accession #: P01106; P01107; Q14026; A8WFE7
• Molecular Weight: 50,565 Da
• NCBI Official Full Name: myc proto-oncogene protein
• NCBI Official Synonym Full Names: v-myc avian myelocytomatosis viral oncogene homolog
• NCBI Official Symbol: MYC
• NCBI Official Synonym Symbols: MRTL; MYCC; c-Myc; bHLHe39
• NCBI Protein Information: myc proto-oncogene protein
• UniProt Protein Name: Myc proto-oncogene protein
• UniProt Gene Name: MYC
• UniProt Synonym Gene Names: BHLHE39; bHLHe39
• UniProt Entry Name: MYC_HUMAN