IHC (Immunohistochemistry)
(IHC staining of distal segment of ligated (7 days) sciatic nerve using AAA14716 at 1:2000 dilution.)
Rabbit Myelin Basic Protein, Degraded Polyclonal Antibody | anti-Mbp antibody
Myelin Basic Protein, Degraded (MBP)
Gene Names
Mbp; Mbps
Applications
Immunohistochemistry
Purity
Serum
Synonyms
Myelin Basic Protein, Degraded, Antibody; Myelin Basic Protein, Degraded (MBP); Anti -Myelin Basic Protein, Degraded (MBP); anti-Mbp antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes Myelin Basic Protein in demyelinated nerve tissues. High specificity for lesioned rat spinal cord.
Purity/Purification
Serum
Form/Format
Supplied as a lyophilized powder. Reconstitute with 50ul of sterile ddH2O. Preservative free.
Applicable Applications for anti-Mbp antibody
Immunohistochemistry (IHC)
Application Notes
Suitable for use in Immunohistochemistry.
Other applications not tested
Dilution: Immunohistochemistry: 1:2000. Immunostains myelin basic protein of abnormal appearing oligodendrocytic processes and cell bodies in demyelinating areas. Recognizes only areas of myelin degeneration when tested in injured spinal cord and lesioned sciatic nerve. It also stains discrete white matter in brain of multiple system atrophy.
Optimal dilution determined by the researcher.
Other applications not tested
Dilution: Immunohistochemistry: 1:2000. Immunostains myelin basic protein of abnormal appearing oligodendrocytic processes and cell bodies in demyelinating areas. Recognizes only areas of myelin degeneration when tested in injured spinal cord and lesioned sciatic nerve. It also stains discrete white matter in brain of multiple system atrophy.
Optimal dilution determined by the researcher.
Immunogen
Synthetic peptide corresponding to amino acids 69-86 of the guinea pig Myelin Basic Protein
Species Cross Reactivity
Human and Rat
Preparation and Storage
Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
IHC (Immunohistochemistry)
(IHC staining of distal segment of ligated (7 days) sciatic nerve using AAA14716 at 1:2000 dilution.)
IHC (Immunohistochemistry)
(IHC staining of distal segment of ligated (7 days) sciatic nerve using AAA14716 at 1:2000 dilution.)
Related Product Information for anti-Mbp antibody
Myelin basic protein (MBP) is a single-chain, flexible polypeptide of about 18.5kD existing in its natural environment as an extrinsic and loosely bound component of the cytoplasmic portion of the myelin membrane sandwich. Ultrastructural immunocytochemistry with anti-myelin basic protein has shown that MBP is localized in the compact myelin sheath. MBP has not been demonstrated in rough endoplasmic reticulum, lysosomes or any other cytoplasmic organelles. MBP serves as a marker for oligodendrocytes and Schwann cells. MBP is also a marker for malignant schwannomas and appears to play a significant role in the etiology of multiple sclerosis and experimental autoimmune encephalomyelitis.
Product Categories/Family for anti-Mbp antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
myelin basic protein isoform 4
NCBI Official Synonym Full Names
myelin basic protein
NCBI Official Symbol
Mbp
NCBI Official Synonym Symbols
Mbps
NCBI Protein Information
Golli-Mbp; myelin basic protein; MBP S; myelin basic protein S; myelin basic protein Golli-mbp; Golli-Mbp; myelin basic protein; myelin basic protein S
UniProt Protein Name
Myelin basic protein S
UniProt Gene Name
Mbp
UniProt Entry Name
MBP_RAT
Similar Products
Product Notes
The Mbp mbp (Catalog #AAA14716) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Myelin Basic Protein, Degraded can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Suitable for use in Immunohistochemistry. Other applications not tested Dilution: Immunohistochemistry: 1:2000. Immunostains myelin basic protein of abnormal appearing oligodendrocytic processes and cell bodies in demyelinating areas. Recognizes only areas of myelin degeneration when tested in injured spinal cord and lesioned sciatic nerve. It also stains discrete white matter in brain of multiple system atrophy. Optimal dilution determined by the researcher. Researchers should empirically determine the suitability of the Mbp mbp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Myelin Basic Protein, Degraded, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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