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product-image-AAA284364_IHC13.jpg IHC (Immunohiostchemistry) (MYL3 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MYL3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Rabbit anti-Human MYL3 Polyclonal Antibody | anti-MYL3 antibody

MYL3 Antibody (N-term)

Gene Names
MYL3; CMH8; VLC1; MLC1V; MLC1SB
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MYL3, Antibody; MYL3 Antibody (N-term); Myosin light chain 3; Cardiac myosin light chain 1; CMLC1; Myosin light chain 1; slow-twitch muscle B/ventricular isoform; MLC1SB; Ventricular/slow twitch myosin alkali light chain; MYL3; anti-MYL3 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MYL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MYL3.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.4 (varies by lot)
Sequence Positions
1-30
Sequence Length
195
Applicable Applications for anti-MYL3 antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

IHC (Immunohiostchemistry)

(MYL3 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MYL3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

product-image-AAA284364_IHC13.jpg IHC (Immunohiostchemistry) (MYL3 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MYL3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

WB (Western Blot)

(Western blot analysis of lysates from human skeletal muscle and heart tissue lysates (from left to right), using MYL3 Antibody (N-term). AAA284364 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)

product-image-AAA284364_WB15.jpg WB (Western Blot) (Western blot analysis of lysates from human skeletal muscle and heart tissue lysates (from left to right), using MYL3 Antibody (N-term). AAA284364 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Related Product Information for anti-MYL3 antibody
MYL3 encodes myosin light chain 3, an alkali light chain
also referred to in the literature as both the ventricular isoform
and the slow skeletal muscle isoform. Mutations in MYL3 have been
identified as a cause of mid-left ventricular chamber type
hypertrophic cardiomyopathy.
Product Categories/Family for anti-MYL3 antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Girolami, F., et al. J. Am. Coll. Cardiol. 55(14):1444-1453(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
McLeod, C.J., et al. Am. Heart J. 158(5):799-805(2009)
Kaski, J.P., et al. Circ Cardiovasc Genet 2(5):436-441(2009)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
21932
NCBI Official Full Name
myosin light chain 3
NCBI Official Synonym Full Names
myosin, light chain 3, alkali; ventricular, skeletal, slow
NCBI Official Symbol
MYL3
NCBI Official Synonym Symbols
CMH8; VLC1; MLC1V; MLC1SB
NCBI Protein Information
myosin light chain 3
UniProt Protein Name
Myosin light chain 3
UniProt Gene Name
MYL3
UniProt Synonym Gene Names
CMLC1; MLC1SB
UniProt Entry Name
MYL3_HUMAN

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Product Notes

The MYL3 myl3 (Catalog #AAA284364) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30. The MYL3 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MYL3 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the MYL3 myl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MYL3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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