IHC (Immunohiostchemistry)
(MYOM1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MYOM1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human MYOM1 Polyclonal Antibody | anti-MYOM1 antibody
MYOM1 Antibody (Center)
Gene Names
MYOM1; SKELEMIN
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MYOM1, Antibody; MYOM1 Antibody (Center); Myomesin-1; 190 kDa connectin-associated protein; 190 kDa titin-associated protein; Myomesin family member 1; MYOM1; anti-MYOM1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MYOM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 904-933 amino acids from the Central region of human MYOM1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
904-933
Sequence Length
1,589
Applicable Applications for anti-MYOM1 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(MYOM1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MYOM1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(MYOM1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MYOM1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(MYOM1 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MYOM1 antibody detected the MYOM1 protein (arrow).)
WB (Western Blot)
(MYOM1 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MYOM1 antibody detected the MYOM1 protein (arrow).)
Related Product Information for anti-MYOM1 antibody
The giant protein titin, together with its associated
proteins, interconnects the major structure of sarcomeres, the M
bands and Z discs. The C-terminal end of the titin string extends
into the M line, where it binds tightly to M-band constituents of
apparent molecular masses of 190 kD (myomesin 1) and 165 kD
(myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and
other myofibrillar proteins contains structural modules with strong
homology to either fibronectin type III (motif I) or immunoglobulin
C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique
N-terminal region followed by 12 modules of motif I or motif II, in
the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins
share 50% sequence identity in this repeat-containing region. The
head structure formed by these 2 proteins on one end of the titin
string extends into the center of the M band. The integrating
structure of the sarcomere arises from muscle-specific members of
the superfamily of immunoglobulin-like proteins. Alternatively
spliced transcript variants encoding different isoforms have been
identified.
proteins, interconnects the major structure of sarcomeres, the M
bands and Z discs. The C-terminal end of the titin string extends
into the M line, where it binds tightly to M-band constituents of
apparent molecular masses of 190 kD (myomesin 1) and 165 kD
(myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and
other myofibrillar proteins contains structural modules with strong
homology to either fibronectin type III (motif I) or immunoglobulin
C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique
N-terminal region followed by 12 modules of motif I or motif II, in
the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins
share 50% sequence identity in this repeat-containing region. The
head structure formed by these 2 proteins on one end of the titin
string extends into the center of the M band. The integrating
structure of the sarcomere arises from muscle-specific members of
the superfamily of immunoglobulin-like proteins. Alternatively
spliced transcript variants encoding different isoforms have been
identified.
Product Categories/Family for anti-MYOM1 antibody
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Schoenauer, R., et al. J. Mol. Biol. 349(2):367-379(2005)
Hornemann, T., et al. J. Mol. Biol. 332(4):877-887(2003)
Porter, J.D., et al. J. Exp. Biol. 206 (PT 17), 3101-3112 (2003) :
Agarkova, I., et al. J. Biol. Chem. 275(14):10256-10264(2000)
Schoenauer, R., et al. J. Mol. Biol. 349(2):367-379(2005)
Hornemann, T., et al. J. Mol. Biol. 332(4):877-887(2003)
Porter, J.D., et al. J. Exp. Biol. 206 (PT 17), 3101-3112 (2003) :
Agarkova, I., et al. J. Biol. Chem. 275(14):10256-10264(2000)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
187627
NCBI Official Full Name
myomesin-1 isoform a
NCBI Official Synonym Full Names
myomesin 1
NCBI Official Symbol
MYOM1
NCBI Official Synonym Symbols
SKELEMIN
NCBI Protein Information
myomesin-1
UniProt Protein Name
Myomesin-1
UniProt Gene Name
MYOM1
UniProt Entry Name
MYOM1_HUMAN
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Product Notes
The MYOM1 myom1 (Catalog #AAA290357) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 904-933. The MYOM1 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MYOM1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the MYOM1 myom1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MYOM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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