Rabbit MYOZAP Polyclonal Antibody | anti-GCOM1 antibody

MYOZAP Antibody

Cat. Num. AAA40212

• Gene Names: GCOM1; gcom; Gcom2; MYZAP; GRINL1A; MYZAP-POLR2M
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: MYOZAP Antibody is affinity chromatography purified via peptide column.
• Synonyms: MYOZAP, Antibody; MYOZAP Antibody; MYOZAP; gcom; Gcom2; MYZAP; GRINL1A; MYZAP-POLR2M; Myocardial zonula adherens protein; GRINL1A upstream protein; Gup; GRINL1A complex locus; anti-GCOM1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Multiple isoforms of MYOZAP are known to exist.
• Purity/Purification: MYOZAP Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 550

• Applicable Applications for anti-GCOM1 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: MYOZAP antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human MYOZAP.
• Buffer: MYOZAP Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: MYOZAP antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of MYOZAP in human lung tissue with MYOZAP antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of MYOZAP in human lung tissue with MYOZAP antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of MYOZAP in rat kidney tissue lysate with MYOZAP antibody at (A) 1 and (B) 2 μg/mL.)

Related Product Information for anti-GCOM1 antibody

MYOZAP Antibody: MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.

NCBI and Uniprot Product Information

• NCBI GI #: 70166414
• NCBI GeneID: 145781
• NCBI Accession #: NP_001018110
• NCBI GenBank Nucleotide #: NM_001018090.6
• UniProt Accession #: P0CAP1; Q6EER8; Q6EES2; Q6EEV3; Q6EF00; Q6EF01; Q6EF02; Q6EF46; Q6EFN8; Q6EM48; Q6K046; D2E9U7
• Molecular Weight: 64,046 Da
• NCBI Official Full Name: GRINL1A combined protein isoform 1
• NCBI Official Synonym Full Names: GRINL1A complex locus 1
• NCBI Official Symbol: GCOM1
• NCBI Official Synonym Symbols: gcom; Gcom2; MYZAP; GRINL1A; MYZAP-POLR2M
• NCBI Protein Information: GRINL1A combined protein; MYZAP-POLR2M protein; MYZAP-POLR2M readthrough; GRINL1A combined protein Gcom12; NMDAR1 subunit-interacting protein; myocardial zonula adherens protein; glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A combined protein
• UniProt Protein Name: Myocardial zonula adherens protein
• UniProt Gene Name: MYZAP
• UniProt Synonym Gene Names: MYOZAP; Gup
• UniProt Entry Name: MYZAP_HUMAN