WB (Western Blot)
(N-Myc antibody (pAb) tested by Western blot. Nuclear extract (20 ug) of Kelly cells probed with N-Myc antibody at a dilution of 1:1,000)
Rabbit anti-Human N-Myc Polyclonal Antibody | anti-N-Myc antibody
N-Myc antibody (pAb)
Gene Names
MYCN; NMYC; ODED; MODED; N-myc; bHLHe37
Reactivity
Human
Applications
Western Blot, Chromatin Immunoprecipitation, Immunoprecipitation
Purity
Affinity Purified
Synonyms
N-Myc, Antibody; N-Myc antibody (pAb); MYCN; NMYC; ODED; MODED; MYCNOT; bHLHe37; anti-N-Myc antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purified
Form/Format
Purified IgG in 70mM Tris (pH8), 105mM NaCl, 31mM glycine, 0.07mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
Applicable Applications for anti-N-Myc antibody
WB (Western Blot), ChIP (Chromatin immunoprecipitation)
Immunogen
This N-Myc antibody was raised against a peptide derived from the C-terminal region of human N-Myc.
Preparation and Storage
Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20 degree C for up to 2 years. Keep all reagents on ice when not in storage.1ug/ul
WB (Western Blot)
(N-Myc antibody (pAb) tested by Western blot. Nuclear extract (20 ug) of Kelly cells probed with N-Myc antibody at a dilution of 1:1,000)
WB (Western Blot)
(N-Myc antibody (pAb) tested by Western blot. Nuclear extract (20 ug) of Kelly cells probed with N-Myc antibody at a dilution of 1:1,000)
ChIP (Chromatin Immunoprecipitation)
(N-Myc antibody (pAb) tested by ChIP-Seq Chromatin immunoprecipitation (ChIP) was performed using the ChIP-IT High Sensitivity Kit with 200 ug of chromatin from human cell line chromatin and 20 ug N-Myc antibody. ChIP DNA was sequenced on the Illumina HiSeq and 9.2 million sequence tags were mapped to identify N-Myc binding sites on chromosome 3. You can view the complete data set in the UCSC Genome Browser, starting at this specific location, here.)
ChIP (Chromatin Immunoprecipitation)
(N-Myc antibody (pAb) tested by ChIP-Seq Chromatin immunoprecipitation (ChIP) was performed using the ChIP-IT High Sensitivity Kit with 200 ug of chromatin from human cell line chromatin and 20 ug N-Myc antibody. ChIP DNA was sequenced on the Illumina HiSeq and 9.2 million sequence tags were mapped to identify N-Myc binding sites on chromosome 3. You can view the complete data set in the UCSC Genome Browser, starting at this specific location, here.)
Related Product Information for anti-N-Myc antibody
Short Description: Our N-Myc antibody (pAb) was raised in a Rabbit host. It has been validated for use in ChIP-Seq and Western blot; it has been shown to react with Human samples.
Background: N-Myc (MYCN) is a member of the Myc family of proto-oncogenes. Myc family members play crucial roles in regulating cell proliferation, size and differentiation. N-Myc is required for proper development of the nervous system. Myc family proteins can induce malignant transformation inappropriately modulating gene transcription, leading to unchecked cell proliferation. Misexpression of N-Myc is often associated with pediatric neural cancers such as neuroblastoma, medulloblastoma and retinoblastoma.
Background: N-Myc (MYCN) is a member of the Myc family of proto-oncogenes. Myc family members play crucial roles in regulating cell proliferation, size and differentiation. N-Myc is required for proper development of the nervous system. Myc family proteins can induce malignant transformation inappropriately modulating gene transcription, leading to unchecked cell proliferation. Misexpression of N-Myc is often associated with pediatric neural cancers such as neuroblastoma, medulloblastoma and retinoblastoma.
Product Categories/Family for anti-N-Myc antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50kDa
NCBI Official Full Name
N-myc proto-oncogene protein isoform 1
NCBI Official Synonym Full Names
MYCN proto-oncogene, bHLH transcription factor
NCBI Official Symbol
MYCN
NCBI Official Synonym Symbols
NMYC; ODED; MODED; N-myc; bHLHe37
NCBI Protein Information
N-myc proto-oncogene protein
UniProt Protein Name
N-myc proto-oncogene protein
UniProt Gene Name
MYCN
UniProt Synonym Gene Names
BHLHE37; NMYC; bHLHe37
UniProt Entry Name
MYCN_HUMAN
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Product Notes
The N-Myc mycn (Catalog #AAA59989) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The N-Myc antibody (pAb) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's N-Myc can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ChIP (Chromatin immunoprecipitation). Researchers should empirically determine the suitability of the N-Myc mycn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "N-Myc, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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