IHC (Immunohiostchemistry)
(Immunohistochemistry of NALP12 in human brain tissue with NALP12 antibody at 5 ug/mL.)
Rabbit NALP12 Polyclonal Antibody | anti-NALP12 antibody
NALP12 Antibody
Gene Names
NLRP12; RNO; PAN6; RNO2; FCAS2; NALP12; PYPAF7; CLR19.3
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
NALP12, Antibody; NALP12 Antibody; NACHT, LRR and PYD domains-containing protein 12, NLRP12, FCAS2, CLR19.3, PAN6, PYPAF7, RNO, RNO2, Monarch-1; anti-NALP12 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
1061
Applicable Applications for anti-NALP12 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against an 18 amino acid peptide near the amino terminus of human NALP12.
Target Name
NALP12
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of NALP12 in human brain tissue with NALP12 antibody at 5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of NALP12 in human brain tissue with NALP12 antibody at 5 ug/mL.)
WB (Western Blot)
(Western blot analysis of NALP12 in human brain tissue lysate with NALP12 antibody at 1 ug/mL.)
WB (Western Blot)
(Western blot analysis of NALP12 in human brain tissue lysate with NALP12 antibody at 1 ug/mL.)
Related Product Information for anti-NALP12 antibody
NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.
Product Categories/Family for anti-NALP12 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
120,329 Da
NCBI Official Full Name
NACHT, LRR and PYD domains-containing protein 12 isoform 2
NCBI Official Synonym Full Names
NLR family, pyrin domain containing 12
NCBI Official Symbol
NLRP12
NCBI Official Synonym Symbols
RNO; PAN6; RNO2; FCAS2; NALP12; PYPAF7; CLR19.3
NCBI Protein Information
NACHT, LRR and PYD domains-containing protein 12
UniProt Protein Name
NACHT, LRR and PYD domains-containing protein 12
UniProt Gene Name
NLRP12
UniProt Synonym Gene Names
NALP12; PYPAF7; RNO
UniProt Entry Name
NAL12_HUMAN
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Product Notes
The NALP12 nlrp12 (Catalog #AAA305365) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NALP12 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NALP12 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the NALP12 nlrp12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NALP12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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