IHC (Immunohiostchemistry)
(Immunohistochemistry of NALP5 in human brain tissue with NALP5 antibody at 10 ug/mL.)
Rabbit NALP5 Polyclonal Antibody | anti-NALP5 antibody
NALP5 Antibody
Gene Names
NLRP5; MATER; NALP5; PAN11; PYPAF8; CLR19.8
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
NALP5, Antibody; NALP5 Antibody; NLR family pyrin domain containing 5, NLRP5, MATER, PYRIN-containing APAF1-like protein 8, PYPAF8, CLR19.8, PAN11; anti-NALP5 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
1200
Applicable Applications for anti-NALP5 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 14 amino acid peptide near the carboxy terminus of human NALP5.
Target Name
NALP5
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of NALP5 in human brain tissue with NALP5 antibody at 10 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of NALP5 in human brain tissue with NALP5 antibody at 10 ug/mL.)
WB (Western Blot)
(Western blot analysis of NALP5 in mouse brain tissue lysate with NALP5 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
WB (Western Blot)
(Western blot analysis of NALP5 in mouse brain tissue lysate with NALP5 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-NALP5 antibody
NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.
Product Categories/Family for anti-NALP5 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
134,342 Da
NCBI Official Full Name
NACHT, LRR and PYD domains-containing protein 5
NCBI Official Synonym Full Names
NLR family, pyrin domain containing 5
NCBI Official Symbol
NLRP5
NCBI Official Synonym Symbols
MATER; NALP5; PAN11; PYPAF8; CLR19.8
NCBI Protein Information
NACHT, LRR and PYD domains-containing protein 5
UniProt Protein Name
NACHT, LRR and PYD domains-containing protein 5
UniProt Gene Name
NLRP5
UniProt Synonym Gene Names
MATER; NALP5
UniProt Entry Name
NALP5_HUMAN
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Product Notes
The NALP5 nlrp5 (Catalog #AAA307753) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NALP5 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NALP5 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the NALP5 nlrp5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NALP5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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