Rabbit Nanos2 Polyclonal Antibody | anti-NANOS2 antibody

Nanos2 Antibody

Cat. Num. AAA39743

• Gene Names: NANOS2; NOS2
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: Nanos2 Antibody is affinity chromatography purified via peptide column.
• Synonyms: Nanos2, Antibody; Nanos2 Antibody; Nanos2; NOS2; Nanos homolog 2; NOS-2; nanos homolog 2 (Drosophila); anti-NANOS2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Nanos2 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 138

• Applicable Applications for anti-NANOS2 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: Nanos2 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of the human Nanos2.
• Buffer: Nanos2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: Nanos2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of Nanos2 in Human Testis cells with Nanos2 antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of Nanos2 in human brain tissue cells with Nanos2 antibody at 2.5 μg/mL.)

WB (Western Blot)

(Western blot analysis of Nanos2 in rat brain tissue lysate with Nanos2 antibody at (A) 1 and (B) 2 μg/mL.)

Related Product Information for anti-NANOS2 antibody

Nanos2 Antibody: Nanos is a zinc-finger containing, RNA-binding protein that has been implicated in germ cell development in both invertebrates and vertebrates. In Drosophila, Nanos represses apoptosis during development to ensure proper germ-line development. Unlike Nanos1 whose expression in mice is dispensable, the Nanos2 and Nanos3 proteins are required for germ cell development. Nanos2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while Nanos3-null PGCs are lost during the migration stage regardless of sex. Nanos2 and Nanos3 have distinct expression patterns during embryo development, suggesting that these two proteins do not have redundant functions. However, expression of Nanos2 can at least partially replace Nanos3 function in a Nanos3-null background. Nanos3 expression can not rescue Nanos2-null defects. This Nanos2 antibody will not cross-react with either Nanos 1 or Nanos3.

NCBI and Uniprot Product Information

• NCBI GI #: 41688561
• NCBI GeneID: 339345
• UniProt Accession #: P60321; Q17R30; Q4G0P8
• Molecular Weight: 15,132 Da
• NCBI Official Full Name: Nanos homolog 2
• NCBI Official Synonym Full Names: nanos homolog 2 (Drosophila)
• NCBI Official Symbol: NANOS2
• NCBI Official Synonym Symbols: NOS2
• NCBI Protein Information: nanos homolog 2; NOS-2
• UniProt Protein Name: Nanos homolog 2
• UniProt Gene Name: NANOS2
• UniProt Synonym Gene Names: NOS2; NOS-2
• UniProt Entry Name: NANO2_HUMAN