Rabbit NCX1 Polyclonal Antibody | anti-NCX1 antibody
NCX1 Polyclonal Antibody
Gene Names
SLC8A1; NCX1
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Synonyms
NCX1, Antibody; NCX1 Polyclonal Antibody; SLC8A1; CNC; NCX1; Sodium/calcium exchanger 1; Na (+)/Ca (2+)-exchange protein 1; anti-NCX1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Applicable Applications for anti-NCX1 antibody
WB (Western Blot)
Cellular Location
Cell membrane; Multi-pass membrane protein
Tissue Location
Detected primarily in heart and at lower levels in brain (PubMed:1374913). Expressed in cardiac sarcolemma, brain, kidney, liver, pancreas, skeletal muscle, placenta and lung (PubMed:1476165)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Related Product Information for anti-NCX1 antibody
Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes (PubMed:1374913, PubMed:11241183, PubMed:1476165). Contributes to Ca(2+) transport during excitation-contraction coupling in muscle. In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels rapidly return to baseline. Required for normal embryonic heart development and the onset of heart contractions.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
108,547 Da
NCBI Official Full Name
Na+/Ca2+ exchanger
NCBI Official Synonym Full Names
solute carrier family 8 (sodium/calcium exchanger), member 1
NCBI Official Symbol
SLC8A1
NCBI Official Synonym Symbols
NCX1
NCBI Protein Information
sodium/calcium exchanger 1; Na+/Ca++ exchanger; Na+/Ca2+ exchanger; Na(+)/Ca(2+)-exchange protein 1
UniProt Protein Name
Sodium/calcium exchanger 1
UniProt Gene Name
SLC8A1
UniProt Synonym Gene Names
CNC; NCX1
UniProt Entry Name
NAC1_HUMAN
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Product Notes
The NCX1 slc8a1 (Catalog #AAA296105) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NCX1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NCX1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the NCX1 slc8a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NCX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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