IHC (Immunohiostchemistry)
(Immunochemical staining of human NDUFA2 in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human NDUFA2 Polyclonal Antibody | anti-NDUFA2 antibody
Anti-NDUFA2 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
NDUFA2, Antibody; Anti-NDUFA2 Antibody, Rabbit Polyclonal; NDUFA2 Antibody, Rabbit PAb, Antigen Affinity Purified; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa; Anti-B8 Antibody; Anti-CD14 Antibody; Anti-CIB8 Antibody; anti-NDUFA2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human NDUFA2
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-NDUFA2 antibody
IHC (Immunohistochemistry)
Immunogen
E Coli-derived Human NDUFA2 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human NDUFA2 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Immunochemical staining of human NDUFA2 in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohiostchemistry)
(Immunochemical staining of human NDUFA2 in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohistochemistry)
(Immunochemical staining of human NDUFA2 in human brain with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohistochemistry)
(Immunochemical staining of human NDUFA2 in human brain with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-NDUFA2 antibody
NDUFA2 (NADH: Ubiquinone Oxidoreductase Subunit A2) is a Protein Coding gene. The NDUFA2 gene, located on 5q31.3, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat, etc. NDUFA2 belongs to the complex I NDUFA2 subunit family. The encoded protein is a subunit of the hydrophobic protein fraction of the NADH: ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Diseases associated with NDUFA2 include Mitochondrial Complex I Deficiency, Nuclear Type 13 and Leukoencephalopathy, Cystic, Without Megalencephaly. Among its related pathways are GABAergic synapse and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
References
Perrier S, et al. (2018) Recessive mutations in ndufa2 cause mitochondrial leukoencephalopathy. Clin Genet 93 (2): 396-400.Hoefs SJ, et al. (2008) Ndufa2 complex i mutation leads to leigh disease. Am J Hum Genet 82 (6): 1306-1315.Brockmann C, et al. (2004) The oxidized subunit b8 from human complex i adopts a thioredoxin fold. Structure 12 (9): 1645-1654.
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Product Notes
The NDUFA2 (Catalog #AAA256457) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-NDUFA2 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NDUFA2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the NDUFA2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NDUFA2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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