Rabbit NDUFS8 Polyclonal Antibody | anti-NDUFS8 antibody

NDUFS8 Antibody (Center)

Cat. Num. AAA285953

• Gene Names: NDUFS8; TYKY; CI-23k; CI23KD
• Reactivity: Human (Predicted Reactivity: Bovine, C Elegans, Monkey, Mouse)
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Synonyms: NDUFS8, Antibody; NDUFS8 Antibody (Center); NADH dehydrogenase [ubiquinone] iron-sulfur protein 8; mitochondrial; Complex I-23kD; CI-23kD; NADH-ubiquinone oxidoreductase 23 kDa subunit; TYKY subunit; NDUFS8; anti-NDUFS8 antibody

• Host: Rabbit
• Reactivity: Human (Predicted Reactivity: Bovine, C Elegans, Monkey, Mouse)
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Specificity: This NDUFS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the Central region of human NDUFS8.
• Purity/Purification: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: Vial Concentration: 0.48 (varies by lot)
• Sequence Positions: 81-108
• Sequence Length: 210

• Applicable Applications for anti-NDUFS8 antibody: IHC (Immunohistochemistry), ELISA, WB (Western Blot)
• Antigen Type: Synthetic Peptide
• Antigen Source: HUMAN
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

IHC (Immunohiostchemistry)

(NDUFS8 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NDUFS8 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

WB (Western Blot)

(NDUFS8 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the NDUFS8 antibody detected the NDUFS8 protein (arrow).)

Related Product Information for anti-NDUFS8 antibody

This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.

Product Categories/Family for anti-NDUFS8 antibody

Cancer; Metabolism; Signal Transduction

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Bourges, I., et al. Biochem. J. 383 (PT 3), 491-499 (2004) : Procaccio, V., et al. Neurology 62(10):1899-1901(2004) Ugalde, C., et al. Hum. Mol. Genet. 13(6):659-667(2004) Murray, J., et al. J. Biol. Chem. 278(39):37223-37230(2003)

NCBI and Uniprot Product Information

• NCBI GI #: 4505371
• NCBI GeneID: 4728
• NCBI Accession #: NP_002487.1
• NCBI GenBank Nucleotide #: NM_002496.3
• UniProt Accession #: O00217; Q0VDA8; B2RB86
• Molecular Weight: 23705
• NCBI Official Full Name: NADH dehydrogenase
• NCBI Official Synonym Full Names: NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
• NCBI Official Symbol: NDUFS8
• NCBI Official Synonym Symbols: TYKY; CI-23k; CI23KD
• NCBI Protein Information: NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
• UniProt Protein Name: NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
• UniProt Gene Name: NDUFS8
• UniProt Synonym Gene Names: CI-23kD
• UniProt Entry Name: NDUS8_HUMAN