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product-image-AAA214163_IHC13.jpg IHC (Immunohiostchemistry) (Detection of human NEDD4L by immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-NEDD4L (Cat. No. AAA214163) used at a dilution of 1:250 Detection: DAB)

Rabbit anti-Human, Mouse NEDD4L Polyclonal Antibody | anti-NEDD4L antibody

Rabbit anti-NEDD4L IHC Antibody, Affinity Purified

Reactivity
Human, Mouse
Applications
Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
NEDD4L, Antibody; Rabbit anti-NEDD4L IHC Antibody, Affinity Purified; E3 ubiquitin-protein ligase NEDD4-like; PVNH7; RSP5; ubiquitin-protein ligase Rsp5; NEDD4.2; HECT-type E3 ubiquitin transferase NED4L; hNEDD4-2; NEDD4-2; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase; anti-NEDD4L antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Concentration
250ug/ml (varies by lot)
Applicable Applications for anti-NEDD4L antibody
IHC (Immunohistochemistry)
Predicted Reactivity
Rat, Bovine, Dog, Horse, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Naked mole rat, Crab-eating macaque, Zebra finch, White-tufted-ear marmoset, African elephant
Immunogen
Between 300 and 350
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt

IHC (Immunohiostchemistry)

(Detection of human NEDD4L by immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-NEDD4L (Cat. No. AAA214163) used at a dilution of 1:250 Detection: DAB)

product-image-AAA214163_IHC13.jpg IHC (Immunohiostchemistry) (Detection of human NEDD4L by immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-NEDD4L (Cat. No. AAA214163) used at a dilution of 1:250 Detection: DAB)

IHC (Immunohistochemistry)

(Detection of mouse NEDD4L by immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-NEDD4L (Cat. No. AAA214163) used at a dilution of 1:250 Detection: DAB)

product-image-AAA214163_IHC15.jpg IHC (Immunohistochemistry) (Detection of mouse NEDD4L by immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-NEDD4L (Cat. No. AAA214163) used at a dilution of 1:250 Detection: DAB)
Related Product Information for anti-NEDD4L antibody
NEDD4L (neural precursor cell expressed, developmentally down-regulated 4-like) functions as an E3 ubiquitin-protein ligase. NEDD4L inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. It also promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5 [taken from the Universal Protein Resource (UniProt) wwwuniprotorg/uniprot/Q96PU5].
Product Categories/Family for anti-NEDD4L antibody

NCBI and Uniprot Product Information

NCBI GeneID
UniProt Accession #
UniProt Protein Name
E3 ubiquitin-protein ligase NEDD4-like
UniProt Gene Name
NEDD4L
UniProt Synonym Gene Names
KIAA0439; NEDL3

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Product Notes

The NEDD4L nedd4l (Catalog #AAA214163) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-NEDD4L IHC Antibody, Affinity Purified reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NEDD4L can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the NEDD4L nedd4l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NEDD4L, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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