Rabbit anti-Human Neurexin 1 Polyclonal Antibody | anti-NRXN1 antibody
Anti-Human Neurexin 1 DyLight 488 conjugated Antibody
Gene Names
NRXN1; PTHSL2; SCZD17; Hs.22998
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Immunogen Affinity Purified
Synonyms
Neurexin 1, Antibody; Anti-Human Neurexin 1 DyLight 488 conjugated Antibody; Rabbit IgG Polyclonal Anti-Human Neurexin 1 Antibody DyLight 488 Conjugated, Flow Validated; Neurexin-1-beta; Neurexin I-beta; NRXN1; Neurexin 1; anti-NRXN1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
No cross reactivity with other proteins.
Purity/Purification
Immunogen Affinity Purified
Form/Format
Liquid; Each vial contains 50% glycerol, 0.9% NaCL, 0.2% Na2HPO4 0.02% NaN3
Sequence Length
442
Applicable Applications for anti-NRXN1 antibody
FCM/FACS (Flow Cytometry)
Immunogen
E Coli-derived human Neurexin 1 recombinant protein (Position: D141-E294).
Conjugate
DyLight 488
Excitation Wavelength: 488 nm
Emission Wavelength: 515-545nm
Excitation Wavelength: 488 nm
Emission Wavelength: 515-545nm
Preparation and Storage
Store at 2-8 degree C for one year. Protect from light. Do not freeze.
Related Product Information for anti-NRXN1 antibody
Neurexin-1-alpha is a protein that in humans is encoded by the NRXN1 gene. This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca (2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3, 000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia.
References
1. Comoletti, Davide; Flynn Robyn; Jennings Lori L; Chubykin Alexander; Matsumura Takehito; Hasegawa Hana; Südhof Thomas C; Taylor Palmer (Dec 2003). "Characterization of the interaction of a recombinant soluble neuroligin-1 with neurexin-1beta". J. Biol. Chem. United States. 278 (50): 50497-50505. 2. Nguyen T, Südhof TC (1997). "Binding properties of neuroligin 1 and neurexin 1beta reveal function as heterophilic cell adhesion molecules". J. Biol. Chem. 272 (41): 26032-26039.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
neurexin-1 isoform beta3
NCBI Official Synonym Full Names
neurexin 1
NCBI Official Symbol
NRXN1
NCBI Official Synonym Symbols
PTHSL2; SCZD17; Hs.22998
NCBI Protein Information
neurexin-1
UniProt Protein Name
Neurexin-1-beta
UniProt Gene Name
NRXN1
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Product Notes
The NRXN1 nrxn1 (Catalog #AAA124930) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Human Neurexin 1 DyLight 488 conjugated Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Neurexin 1 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the NRXN1 nrxn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Neurexin 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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