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product-image-AAA289903_IHC13.jpg IHC (Immunohiostchemistry) (NFATC1 Antibody (C-term) (AAA289903)immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NFATC1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Rabbit anti-Human NFATC1 Polyclonal Antibody | anti-NFATC1 antibody

NFATC1 Antibody (C-term)

Gene Names
NFATC1; NFAT2; NFATc; NF-ATC; NF-ATc1.2
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
NFATC1, Antibody; NFATC1 Antibody (C-term); Nuclear factor of activated T-cells; cytoplasmic 1; NF-ATc1; NFATc1; NFAT transcription complex cytosolic component; NF-ATc; NFATc; NFATC1; NFAT2; NFATC; anti-NFATC1 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This NFATC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 898-927 amino acids from the C-terminal region of human NFATC1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
898-927
Sequence Length
353
Applicable Applications for anti-NFATC1 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

IHC (Immunohiostchemistry)

(NFATC1 Antibody (C-term) (AAA289903)immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NFATC1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

product-image-AAA289903_IHC13.jpg IHC (Immunohiostchemistry) (NFATC1 Antibody (C-term) (AAA289903)immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NFATC1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

WB (Western Blot)

(NFATC1 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the NFATC1 antibody detected the NFATC1 protein (arrow).)

product-image-AAA289903_WB15.jpg WB (Western Blot) (NFATC1 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the NFATC1 antibody detected the NFATC1 protein (arrow).)
Related Product Information for anti-NFATC1 antibody
The product of this gene is a component of the nuclear
factor of activated T cells DNA-binding transcription complex. This
complex consists of at least two components: a preexisting
cytosolic component that translocates to the nucleus upon T cell
receptor (TCR) stimulation, and an inducible nuclear component.
Proteins belonging to this family of transcription factors play a
central role in inducible gene transcription during immune
response. The product of this gene is an inducible nuclear
component. It functions as a major molecular target for the
immunosuppressive drugs such as cyclosporin A. Five transcript
variants encoding distinct isoforms have been identified for this
gene. Different isoforms of this protein may regulate inducible
expression of different cytokine genes.
Product Categories/Family for anti-NFATC1 antibody
References
Liu, Y.J., et al. Obesity (Silver Spring) 18(12):2339-2346(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Chen, C., et al. Biocell 34(2):57-63(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Amaral, F.R., et al. J. Oral Pathol. Med. 39(3):269-274(2010)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI GenBank Nucleotide #
Molecular Weight
101243
NCBI Official Full Name
nuclear factor of activated T-cells, cytoplasmic 1 isoform F
NCBI Official Synonym Full Names
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NCBI Official Symbol
NFATC1
NCBI Official Synonym Symbols
NFAT2; NFATc; NF-ATC; NF-ATc1.2
NCBI Protein Information
nuclear factor of activated T-cells, cytoplasmic 1
UniProt Protein Name
Nuclear factor of activated T-cells, cytoplasmic 1
UniProt Gene Name
NFATC1
UniProt Synonym Gene Names
NFAT2; NFATC; NF-ATc1; NFATc1; NF-ATc; NFATc
UniProt Entry Name
NFAC1_HUMAN

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Product Notes

The NFATC1 nfatc1 (Catalog #AAA289903) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 898-927. The NFATC1 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NFATC1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the NFATC1 nfatc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NFATC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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