Rabbit anti-Human NIK Polyclonal Antibody | anti-MAP3K14 antibody

NIK Antibody

Cat. Num. AAA39464

• Gene Names: MAP3K14; HS; NIK; HSNIK; FTDCR1B
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: NIK Antibody is Antibody is DEAE purified.
• Synonyms: NIK, Antibody; NIK Antibody; NIK; HS; HSNIK; FTDCR1B; Mitogen-activated protein kinase kinase kinase 14; NF-kappa-beta-inducing kinase; HsNIK; mitogen-activated protein kinase kinase kinase 14; anti-MAP3K14 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: NIK Antibody is Antibody is DEAE purified.
• Form/Format: Liquid
• Sequence Length: 947

• Applicable Applications for anti-MAP3K14 antibody: WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: NIK antibody was raised against a 17 amino acid peptide near the carboxy terminus of human NIK.
• Buffer: NIK Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: NIK antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of NIK in Hek293 cells with NIK antibody at 20 μg/mL.Green: NIK Antibody (1129)Blue: DAPI staining)

ICC (Immunocytochemistry)

(Immunocytochemistry of NIK in Hek293 cells with NIK antibody at 10 μg/mL.)

Related Product Information for anti-MAP3K14 antibody

NIK Antibody: Nuclear factor kappa B (NF-κB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFα, LPS and mitogens. A serine/threonine protein kinase which mediates NF-κB activation by IL-1, TNFα and CD95 was identified recently and designated NIK (for NF-κB inducing kinase). NIK is an activator of IκB kinase alpha and beta (IKKα and IKKβ). Therefore, NIK is a key molecule in the NF-κB signaling pathway leading to the induction of a variety of gene expression in response to proinflammatory cytokines and bacteria products.

NCBI and Uniprot Product Information

• NCBI GI #: 92090612
• NCBI GeneID: 9020
• UniProt Accession #: Q99558; Q8IYN1; A8K2D8; D3DX67
• Molecular Weight: 104,042 Da
• NCBI Official Full Name: Mitogen-activated protein kinase kinase kinase 14
• NCBI Official Synonym Full Names: mitogen-activated protein kinase kinase kinase 14
• NCBI Official Symbol: MAP3K14
• NCBI Official Synonym Symbols: HS; NIK; HSNIK; FTDCR1B
• NCBI Protein Information: mitogen-activated protein kinase kinase kinase 14; NF-kappa-beta-inducing kinase; serine/threonine-protein kinase NIK
• UniProt Protein Name: Mitogen-activated protein kinase kinase kinase 14
• UniProt Gene Name: MAP3K14
• UniProt Synonym Gene Names: NIK; HsNIK
• UniProt Entry Name: M3K14_HUMAN