IHC (Immunohiostchemistry)
(Immunohistochemistry of NK3R in human brain tissue with NK3R antibody at 5 ug/mL.)
Rabbit anti-Human, Mouse NK3R Polyclonal Antibody | anti-NK3R antibody
NK3R Antibody
Gene Names
TACR3; NKR; HH11; NK3R; NK-3R; TAC3RL
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
NK3R, Antibody; NK3R Antibody; Neurokinin B receptor, NK-3 receptor, NK-3R, Tachykinin receptor 3, TACR3; anti-NK3R antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
465
Applicable Applications for anti-NK3R antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 18 amino acid peptide from near the center of human NK3R.
Target Name
NK3R
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of NK3R in human brain tissue with NK3R antibody at 5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of NK3R in human brain tissue with NK3R antibody at 5 ug/mL.)
WB (Western Blot)
(Western blot analysis of NK3R in RAW264.7 cell lysate with NK3R antibody at (A) 0.5 and (B) 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of NK3R in RAW264.7 cell lysate with NK3R antibody at (A) 0.5 and (B) 2 ug/mL.)
Related Product Information for anti-NK3R antibody
The tachykinins are a family of small peptides that include the neurotransmitters substance P, neurokinin A, and neurokinin B, which can act on three related but distinct seven transmembrane G-proteins coupled receptors, albeit at different concentrations. The NK-3 receptor (NK3R) has greatest affinity for neurokinin B and is highly expressed in the supraoptic and paraventricular nuclei. Following binding of its ligand, NK3R activates a phosphatidylinositol-calcium second messenger system. It is likely these signals lead to the release of vasopressin and oxytocin into the circulation. NK3R may be involved in learning and memory as mice lacking this gene expressed cognitive deficits compared to normal mice. Although it has been suggested that NK3R plays a role in the regulation of vagal afferent relay neurons, it is likely that these receptors are activated by substance P or neurokinin A, as the airway nerves do not express neurokinin B. NK3R antibody does not recognize NK1R or NK2R.
Product Categories/Family for anti-NK3R antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52,202 Da
NCBI Official Full Name
neuromedin-K receptor
NCBI Official Synonym Full Names
tachykinin receptor 3
NCBI Official Symbol
TACR3
NCBI Official Synonym Symbols
NKR; HH11; NK3R; NK-3R; TAC3RL
NCBI Protein Information
neuromedin-K receptor
UniProt Protein Name
Neuromedin-K receptor
UniProt Gene Name
TACR3
UniProt Synonym Gene Names
NK3R; TAC3R; NKR; NK-3R
UniProt Entry Name
NK3R_HUMAN
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Product Notes
The NK3R tacr3 (Catalog #AAA302792) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NK3R Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NK3R can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the NK3R tacr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NK3R, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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