IF (Immunofluorescence)
(Immunofluorescence analysis of U2OS cells using NLRP2 antibody.)
Rabbit anti-Human NLRP2 Polyclonal Antibody | anti-NLRP2 antibody
NLRP2 Polyclonal Antibody
Gene Names
NLRP2; NBS1; PAN1; NALP2; PYPAF2; CLR19.9
Reactivity
Human
Applications
Immunofluorescence, Western Blot
Purity
Affinity purification
Synonyms
NLRP2, Antibody; NLRP2 Polyclonal Antibody; NLRP2; CLR19.9; NALP2; NBS1; PAN1; PYPAF2; NLR family pyrin domain containing 2; anti-NLRP2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 50% glycerol, pH7.4
Applicable Applications for anti-NLRP2 antibody
IF (Immunofluorescence), WB (Western Blot)
Immunogen
Recombinant fusion protein of human NLRP2 (NP_060322.1).
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
IF (Immunofluorescence)
(Immunofluorescence analysis of U2OS cells using NLRP2 antibody.)
IF (Immunofluorescence)
(Immunofluorescence analysis of U2OS cells using NLRP2 antibody.)
WB (Western Blot)
(Western blot analysis of extracts of A-549 cells, using NLRP2 antibody.)
WB (Western Blot)
(Western blot analysis of extracts of A-549 cells, using NLRP2 antibody.)
Related Product Information for anti-NLRP2 antibody
This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product Categories/Family for anti-NLRP2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
117,883 Da
NCBI Official Full Name
NACHT, LRR and PYD domains-containing protein 2 isoform 1
NCBI Official Synonym Full Names
NLR family, pyrin domain containing 2
NCBI Official Symbol
NLRP2
NCBI Official Synonym Symbols
NBS1; PAN1; NALP2; PYPAF2; CLR19.9
NCBI Protein Information
NACHT, LRR and PYD domains-containing protein 2; nucleotide-binding site protein 1; PYRIN-containing APAF1-like protein 2; NACHT, LRR and PYD containing protein 2; NACHT, leucine rich repeat and PYD containing 2; PYRIN domain and NACHT domain-containing p
UniProt Protein Name
NACHT, LRR and PYD domains-containing protein 2
UniProt Gene Name
NLRP2
UniProt Synonym Gene Names
NALP2; NBS1; PAN1; PYPAF2
UniProt Entry Name
NALP2_HUMAN
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Product Notes
The NLRP2 nlrp2 (Catalog #AAA311634) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NLRP2 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NLRP2 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the NLRP2 nlrp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NLRP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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