IF (Immunofluorescence)
(Immunofluorescence of NOD3 in Jurkat cells with NOD3 antibody at 20 μg/mL.)
Rabbit NOD3 Polyclonal Antibody | anti-NLRC3 antibody
NOD3 Antibody
Gene Names
NLRC3; NOD3; CLR16.2
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot, ELISA
Purity
NOD3 Antibody is affinity chromatography purified via peptide column.
Synonyms
NOD3, Antibody; NOD3 Antibody; NOD3; CLR16.2; Protein NLRC3; CARD15-like protein; NLR family, CARD domain containing 3; anti-NLRC3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
NOD3 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1112
Applicable Applications for anti-NLRC3 antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
NOD3 antibody was raised against an 18 amino acid synthetic peptide near the center of human NOD3.
Buffer
NOD3 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of NOD3 in Jurkat cells with NOD3 antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of NOD3 in Jurkat cells with NOD3 antibody at 20 μg/mL.)
WB (Western Blot)
(Western blot analysis of NOD3 in 3T3 cell lysate with NOD3 antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of NOD3 in 3T3 cell lysate with NOD3 antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-NLRC3 antibody
NOD3 Antibody: NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD3 also known as NLR family CARD containing 3 (NLRC3), is predominantly expressed in the immune system, particularly in T lymphocytes, and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating the activation of T cells. NOD3 inhibits NF-kappaB, AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
111,634 Da
NCBI Official Full Name
NOD3 protein, isoform CRA_d
NCBI Official Synonym Full Names
NLR family, CARD domain containing 3
NCBI Official Symbol
NLRC3
NCBI Official Synonym Symbols
NOD3; CLR16.2
NCBI Protein Information
protein NLRC3; CARD15-like protein; NOD-like receptor C3; caterpiller protein 16.2; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 3
UniProt Protein Name
Protein NLRC3
UniProt Gene Name
NLRC3
UniProt Synonym Gene Names
NOD3; CLR16.2
UniProt Entry Name
NLRC3_HUMAN
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Product Notes
The NLRC3 nlrc3 (Catalog #AAA39427) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NOD3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NOD3 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the NLRC3 nlrc3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NOD3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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