IF (Immunofluorescence)
(Immunofluorescence of NOX4 in human spleen tissue with NOX4 antibody at 20 μg/ml.)
Rabbit NOX4 Polyclonal Antibody | anti-NOX4 antibody
NOX4 Antibody
Gene Names
NOX4; KOX; KOX-1; RENOX
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
NOX4 antibody is affinity chromatography purified via peptide column.
Synonyms
NOX4, Antibody; NOX4 Antibody; NAPDH oxidase 4; NOX-4; RENOX; KOX; KOX-1; NADPH oxidase 4; anti-NOX4 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
NOX4 antibody is human, mouse, and rat reactive. At least four isoforms of NOX4 are known to exist. NOX4 is predicted to not cross-react with other NOX proteins.
Purity/Purification
NOX4 antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
578
Applicable Applications for anti-NOX4 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
NOX4 antibody was raised against a 14 amino acid peptide near the amino terminus of human NOX4.
Buffer
NOX4 antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
NOX4 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IF (Immunofluorescence)
(Immunofluorescence of NOX4 in human spleen tissue with NOX4 antibody at 20 μg/ml.)
IF (Immunofluorescence)
(Immunofluorescence of NOX4 in human spleen tissue with NOX4 antibody at 20 μg/ml.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of NOX4 in human spleen tissue with NOX4 antibody at 5 μg/ml.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of NOX4 in human spleen tissue with NOX4 antibody at 5 μg/ml.)
WB (Western Blot)
(Western blot analysis of NOX4 in Jurkat cell lysate with NOX4 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
WB (Western Blot)
(Western blot analysis of NOX4 in Jurkat cell lysate with NOX4 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-NOX4 antibody
The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide (1). NOX4 is is expressed in multiple tissues and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS) (2,3). Unlike other NOX proteins, NOX4 does not require cytosolic subunits and thus is constitutively active (4). The function of NOX4 remains unclear as it plays both protective and deleterious roles in cellular metabolism.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 64 kDa
Observed: 68 kDa
Observed: 68 kDa
NCBI Official Full Name
NADPH oxidase 4 isoform a
NCBI Official Synonym Full Names
NADPH oxidase 4
NCBI Official Symbol
NOX4
NCBI Official Synonym Symbols
KOX; KOX-1; RENOX
NCBI Protein Information
NADPH oxidase 4; kidney oxidase-1; renal NAD(P)H-oxidase; kidney superoxide-producing NADPH oxidase
UniProt Protein Name
NADPH oxidase 4
UniProt Gene Name
NOX4
UniProt Synonym Gene Names
RENOX; KOX-1
UniProt Entry Name
NOX4_HUMAN
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Product Notes
The NOX4 nox4 (Catalog #AAA40602) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NOX4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NOX4 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the NOX4 nox4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NOX4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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