IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using NPRL2 Polyclonal Antibody at dilution 1:50)
Rabbit NPRL2 Polyclonal Antibody | anti-NPRL2 antibody
NPRL2 Polyclonal Antibody
Gene Names
NPRL2; NPR2; NPR2L; TUSC4
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, ELISA
Purity
Antigen affinity purification
Synonyms
NPRL2, Antibody; NPRL2 Polyclonal Antibody; NPR2; NPR2L; TUSC4; anti-NPRL2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
2.9mg/mL (varies by lot)
Sequence Length
380
Applicable Applications for anti-NPRL2 antibody
IHC (Immunohistochemistry), ELISA
Immunogen
Synthetic peptide of human NPRL2
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using NPRL2 Polyclonal Antibody at dilution 1:50)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using NPRL2 Polyclonal Antibody at dilution 1:50)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NPRL2 Polyclonal Antibody at dilution 1:50)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NPRL2 Polyclonal Antibody at dilution 1:50)
Related Product Information for anti-NPRL2 antibody
NPRL2, also known as TUSC4 (tumor suppressor candidate 4), is a 380 amino acid protein that contains a bipartite nuclear localization signal and a granulin protein-binding domain. It is highly expressed in skeletal muscle, followed by brain, liver and pancreas, with lower expression in lung, kidney, placenta and heart. NPRL2 is also expressed in most lung cancer cell lines and may be involved in tumor suppression. NPRL2 may play a role in mismatch repair, cell cycle checkpoint signaling and activation of apoptotic pathways. It may also enhance the therapeutic efficacy of chemotherapy drugs such as cis-platin by resensitizing patients resistant to cisplatin treatment. The gene encoding NPRL2 is conserved between species and is expressed as two isoforms due to alternative splicing events.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23,150 Da
NCBI Official Full Name
nitrogen permease regulator 2-like protein
NCBI Official Synonym Full Names
nitrogen permease regulator-like 2 (S. cerevisiae)
NCBI Official Symbol
NPRL2
NCBI Official Synonym Symbols
NPR2; NPR2L; TUSC4
NCBI Protein Information
nitrogen permease regulator 2-like protein; 2810446G01Rik; G21 protein; NPR2-like protein; gene 21 protein; homologous to yeast nitrogen permease (candidate tumor suppressor); tumor suppressor candidate 4
UniProt Protein Name
Nitrogen permease regulator 2-like protein
UniProt Gene Name
NPRL2
UniProt Synonym Gene Names
TUSC4; NPR2-like protein; G21 protein
UniProt Entry Name
NPRL2_HUMAN
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Product Notes
The NPRL2 nprl2 (Catalog #AAA168959) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NPRL2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NPRL2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the NPRL2 nprl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NPRL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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