Rabbit NR1I3 Polyclonal Antibody | anti-NR1I3 antibody

NR1I3 Antibody

Cat. Num. AAA301942

• Gene Names: NR1I3; CAR; CAR1; MB67
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: Antibodies were purified by affinity purification using immunogen.
• Synonyms: NR1I3, Antibody; NR1I3 Antibody; CAR; CAR1; MB67; anti-NR1I3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous level of total NR1I3 protein.
• Purity/Purification: Antibodies were purified by affinity purification using immunogen.
• Form/Format: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 340

• Applicable Applications for anti-NR1I3 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen Type: Recombinant Protein
• Immunogen Description: Recombinant protein of human NR1I3.
• Target Name: NR1I3
• Preparation and Storage: Store at -20 degree C

IF (Immunofluorescence)

(Immunofluorescence analysis of U2OS cell using NR1I3 antibody. Blue: DAPI for nuclear staining.)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded rat kidney using NR1I3 antibody at dilution of 1:100 (400x lens).)

IHC (Immunohistochemisry)

(Immunohistochemical analysis of paraffin-embedded human esophagus using NR1I3 antibody at dilution of 1:100 (400x lens).)

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded human esophageal cancer using NR1I3 antibody at dilution of 1:100 (400x lens).)

WB (Western Blot)

(Western blot analysis of extracts of various cell lines, using NR1I3 antibody.)

Related Product Information for anti-NR1I3 antibody

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene

Product Categories/Family for anti-NR1I3 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 117938729
• NCBI GeneID: 9970
• NCBI Accession #: NP_001070937.1
• NCBI GenBank Nucleotide #: NM_001077469.2
• UniProt Accession #: Q14994; Q0VAC9; Q4U0F0; E9PB75; E9PC13; E9PDU3; E9PGH6; E9PH10; E9PHC8; E9PHN4; F1D8Q0; F1D8Q1
• Molecular Weight: SDS-PAGE: 39kD
• NCBI Official Full Name: nuclear receptor subfamily 1 group I member 3 isoform 6
• NCBI Official Synonym Full Names: nuclear receptor subfamily 1, group I, member 3
• NCBI Official Symbol: NR1I3
• NCBI Official Synonym Symbols: CAR; CAR1; MB67
• NCBI Protein Information: nuclear receptor subfamily 1 group I member 3
• UniProt Protein Name: Nuclear receptor subfamily 1 group I member 3
• UniProt Gene Name: NR1I3
• UniProt Synonym Gene Names: CAR; Constitutive active response; CAR
• UniProt Entry Name: NR1I3_HUMAN