Rabbit anti-Human, Mouse Nudel Polyclonal Antibody | anti-NDEL1 antibody

Nudel Antibody

Cat. Num. AAA39258

• Gene Names: NDEL1; EOPA; NDE2; NUDEL; MITAP1; NDE1L1
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: Nudel Antibody is affinity chromatography purified via peptide column.
• Synonyms: Nudel, Antibody; Nudel Antibody; Nudel; EOPA; NDE2; NUDEL; MITAP1; NDE1L1; Nuclear distribution protein nudE-like 1; Mitosin-associated protein 1; Protein Nudel; nudE nuclear distribution gene E homolog (A. nidulans)-like 1; anti-NDEL1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Nudel Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 345

• Applicable Applications for anti-NDEL1 antibody: IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: Nudel antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Nudel.
• Buffer: Nudel Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: Nudel antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of Nudel in Jurkat cells with Nudel antibody at 10 μg/mL.)

ICC (Immunocytochemistry)

(Immunocytochemistry of Nudel in Jurkat cells with Nudel antibody at 2 μg/mL.)

WB (Western Blot)

(Western blot analysis of Nudel in Jurkat whole cell lysate with Nudel antibody at (A) 0.5, (B) 1, or (C) 2 μg/mL.)

Related Product Information for anti-NDEL1 antibody

Nudel Antibody: Nudel was initially discovered as a protein homologous to Aspergillus NUDE and that associated with Lis1 and polyprotein complex cytoplasmic dynein, both of which have been linked to neuronal development and migration. It was later shown to be a substrate of cdk5, a kinase known to be critical during neuronal migration; phosphorylation of Nudel by cdk5 affects its localization in neurons and affects neuritic morphology. It is thought that together with Lis1, Nudel regulates cytoplasmic dynein, a large polyprotein complex, in neuronal migration and mitosis through direct interactions. Similar interactions are thought to also play a role in membrane traffic in other cells as disruption of Nudel expression through RNA interference perturbed normal endomembrane flux and resulted in the fragmentation of the Golgi apparatus.

NCBI and Uniprot Product Information

• NCBI GI #: 12043569
• NCBI GeneID: 81565
• UniProt Accession #: Q9GZM8; Q86T80; Q8TAR7; Q9UH50; B3KP93; D3DTS0; J3QT32
• Molecular Weight: 37,039 Da
• NCBI Official Full Name: Nudel
• NCBI Official Synonym Full Names: nudE neurodevelopment protein 1-like 1
• NCBI Official Symbol: NDEL1
• NCBI Official Synonym Symbols: EOPA; NDE2; NUDEL; MITAP1; NDE1L1
• NCBI Protein Information: nuclear distribution protein nudE-like 1; protein Nudel; endooligopeptidase A; mitosin-associated protein 1; mitosin-associated protein MITAP1; nudE nuclear distribution E homolog-like 1; nudE nuclear distribution gene E homolog-like 1
• UniProt Protein Name: Nuclear distribution protein nudE-like 1
• UniProt Gene Name: NDEL1
• UniProt Synonym Gene Names: EOPA; MITAP1; NUDEL; Protein Nudel
• UniProt Entry Name: NDEL1_HUMAN