IF (Immunofluorescence)
(Immunofluorescence analysis of HeLa cells using OAS1 antibody.)
Rabbit OAS1 Polyclonal Antibody | anti-OAS1 antibody
OAS1 Polyclonal Antibody
Gene Names
OAS1; OIAS; IFI-4; OIASI
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity Purification
Synonyms
OAS1, Antibody; OAS1 Polyclonal Antibody; OIAS; IFI-4; OIASI; anti-OAS1 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Sequence Length
400
Applicable Applications for anti-OAS1 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-364 of human OAS1 (NP_002525.2)
Species Reactivity/ Cross-Reactivity
Human, Mouse
Preparation and Storage
Store at -20°C. Avoid freeze / thaw cycles.
IF (Immunofluorescence)
(Immunofluorescence analysis of HeLa cells using OAS1 antibody.)
IF (Immunofluorescence)
(Immunofluorescence analysis of HeLa cells using OAS1 antibody.)
WB (Western Blot)
(Western blot analysis of extracts of mouse liver, using OAS1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.)
WB (Western Blot)
(Western blot analysis of extracts of mouse liver, using OAS1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.)
Related Product Information for anti-OAS1 antibody
This gene is induced by interferons and encodes a protein that synthesizes 2',5'- oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12.
Product Categories/Family for anti-OAS1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Observed MW: 40kDa
Calculated MW: 41kDa/43kDa/46kDa/47kDa
Calculated MW: 41kDa/43kDa/46kDa/47kDa
NCBI Official Full Name
2'-5'-oligoadenylate synthase 1
NCBI Official Synonym Full Names
2'-5'-oligoadenylate synthetase 1, 40/46kDa
NCBI Official Symbol
OAS1
NCBI Official Synonym Symbols
OIAS; IFI-4; OIASI
NCBI Protein Information
2'-5'-oligoadenylate synthase 1; E18/E16; p46/p42 OAS; 2-5A synthase 1; 2-5A synthetase 1; (2-5')oligo(A) synthase 1; 2',5'-oligo A synthetase 1; (2-5')oligo(A) synthetase 1; 2'-5'-oligoisoadenylate synthetase 1; 2',5'-oligoadenylate synthetase 1, 40/46kDa; 2'-5' oligoadenylate synthetase 1 p48 isoform; 2'-5' oligoadenylate synthetase 1 p52 isoform
UniProt Protein Name
2'-5'-oligoadenylate synthase 1
UniProt Gene Name
OAS1
UniProt Synonym Gene Names
OIAS; (2-5')oligo(A) synthase 1; 2-5A synthase 1
UniProt Entry Name
OAS1_HUMAN
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Product Notes
The OAS1 oas1 (Catalog #AAA37479) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's OAS1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the OAS1 oas1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OAS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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