IHC (Immunohiostchemistry)
(OGDH Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OGDH Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human OGDH Polyclonal Antibody | anti-OGDH antibody
OGDH Antibody (C-term)
Gene Names
OGDH; E1k; OGDC; AKGDH
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
OGDH, Antibody; OGDH Antibody (C-term); 2-oxoglutarate dehydrogenase; mitochondrial; 2-oxoglutarate dehydrogenase complex component E1; OGDC-E1; Alpha-ketoglutarate dehydrogenase; OGDH; anti-OGDH antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This OGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381-410 amino acids from the C-terminal region of human OGDH.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
381-410
Sequence Length
427
Applicable Applications for anti-OGDH antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(OGDH Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OGDH Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(OGDH Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OGDH Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(OGDH Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the OGDH antibody detected the OGDH protein (arrow).)
WB (Western Blot)
(OGDH Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the OGDH antibody detected the OGDH protein (arrow).)
Related Product Information for anti-OGDH antibody
This gene encodes one subunit of the 2-oxoglutarate
dehydrogenase complex. This complex catalyzes the overall
conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA
and CO(2) during the Krebs cycle. The protein is located in the
mitochondrial matrix and uses thiamine pyrophosphate as a cofactor.
A congenital deficiency in 2-oxoglutarate dehydrogenase activity is
believed to lead to hypotonia, metabolic acidosis, and
hyperlactatemia. Alternative splicing results in multiple
transcript variants encoding distinct isoforms.
dehydrogenase complex. This complex catalyzes the overall
conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA
and CO(2) during the Krebs cycle. The protein is located in the
mitochondrial matrix and uses thiamine pyrophosphate as a cofactor.
A congenital deficiency in 2-oxoglutarate dehydrogenase activity is
believed to lead to hypotonia, metabolic acidosis, and
hyperlactatemia. Alternative splicing results in multiple
transcript variants encoding distinct isoforms.
Product Categories/Family for anti-OGDH antibody
References
van Bever, Y., et al. Am. J. Med. Genet. A 143(7):763-767(2007)
Shi, Q., et al. J. Biol. Chem. 280(12):10888-10896(2005)
Habelhah, H., et al. J. Biol. Chem. 279(51):53782-53788(2004)
McCartney, R.G., et al. J. Biol. Chem. 273(37):24158-24164(1998)
Koike, K. Gene 159(2):261-266(1995)
Shi, Q., et al. J. Biol. Chem. 280(12):10888-10896(2005)
Habelhah, H., et al. J. Biol. Chem. 279(51):53782-53788(2004)
McCartney, R.G., et al. J. Biol. Chem. 273(37):24158-24164(1998)
Koike, K. Gene 159(2):261-266(1995)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
115935
NCBI Official Full Name
2-oxoglutarate dehydrogenase, mitochondrial isoform 2
NCBI Official Synonym Full Names
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
NCBI Official Symbol
OGDH
NCBI Official Synonym Symbols
E1k; OGDC; AKGDH
NCBI Protein Information
2-oxoglutarate dehydrogenase, mitochondrial
UniProt Protein Name
2-oxoglutarate dehydrogenase, mitochondrial
UniProt Gene Name
OGDH
UniProt Synonym Gene Names
OGDC-E1
UniProt Entry Name
ODO1_HUMAN
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Product Notes
The OGDH ogdh (Catalog #AAA284947) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 381-410. The OGDH Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's OGDH can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the OGDH ogdh for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OGDH, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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