IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ORC1 Polyclonal Antibody at dilution of 1:65(×200))
Rabbit ORC1 Polyclonal Antibody | anti-ORC1 antibody
ORC1 Polyclonal Antibody
Gene Names
ORC1; ORC1L; PARC1; HSORC1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
ORC1, Antibody; ORC1 Polyclonal Antibody; HSORC1; MmORC1; Orc1; ORC1; ORC1L; Origin Recognition Complex 1; Origin recognition complex subunit 1 (yeast homolog) like; Origin recognition complex subunit 1; Origin recognition complex subunit 1 homolog; Origin recognition complex subunit 1 like (S. cerevisia; Origin recognition complex subunit 1 like; Origin recognition complex subunit 1 S. cerevisiae homolog like; Origin recognition complex; Subunit 1 like (yeast); PARC1; Replication control protein 1; anti-ORC1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
1.14mg/mL (varies by lot)
Sequence Length
861
Applicable Applications for anti-ORC1 antibody
ELISA, IHC (Immunohistochemistry)
Immunogen
Fusion protein of human ORC1
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ORC1 Polyclonal Antibody at dilution of 1:65(×200))
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ORC1 Polyclonal Antibody at dilution of 1:65(×200))
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ORC1 Polyclonal Antibody at dilution of 1:65(×200))
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ORC1 Polyclonal Antibody at dilution of 1:65(×200))
Related Product Information for anti-ORC1 antibody
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is the largest subunit of the ORC complex. While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cell cycle, which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication. This protein is found to be selectively phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1), a protein involved in control of transcription silencing. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.ORC1 (Origin Recognition Complex Subunit 1) is a Protein Coding gene. Diseases associated with ORC1 include Meier-Gorlin Syndrome 1 and Microtia. Among its related pathways are E2F mediated regulation of DNA replication and CDK-mediated phosphorylation and removal of Cdc6. GO annotations related to this gene include chromatin binding. An important paralog of this gene is CDC6.
Product Categories/Family for anti-ORC1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
origin recognition complex subunit 1 isoform 1
NCBI Official Synonym Full Names
origin recognition complex subunit 1
NCBI Official Symbol
ORC1
NCBI Official Synonym Symbols
ORC1L; PARC1; HSORC1
NCBI Protein Information
origin recognition complex subunit 1
UniProt Protein Name
Origin recognition complex subunit 1
UniProt Gene Name
ORC1
UniProt Synonym Gene Names
ORC1L; PARC1
UniProt Entry Name
ORC1_HUMAN
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Product Notes
The ORC1 orc1 (Catalog #AAA176426) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ORC1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ORC1 can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the ORC1 orc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ORC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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